Atherosclerosis, a chronic cardiovascular disease caused by plaque development in
arteries, remains a leading cause of morbidity and mortality. Atherosclerotic plaques are …

Trimethylamine N-oxide (TMAO) is a biologically active gut microbiome-derived dietary
metabolite. Recent studies have shown that high circulating plasma TMAO levels are closely …

Atherosclerosis is an inflammatory disease initiated by endothelial activation, in which
lipoprotein, cholesterol, extracellular matrix, and various types of immune and non-immune …

Technology at the single‐cell level has advanced dramatically in characterizing molecular
heterogeneity. These technologies have enabled cell subtype diversity to be seen in all …

Atherosclerotic cardiovascular disease (ASCVD) represents the major cause of morbidity
and mortality worldwide. The onset of the atherosclerosis process occurs during childhood …

Intracranial aneurysm (IA) is a severe cerebrovascular disease characterized by abnormal
bulging of cerebral vessels that may rupture and cause a stroke. The expansion of the …

Atherosclerosis (AS) is a pathological basis of cardiovascular and cerebrovascular
diseases. A severe global public health problem contributes to the growing burden of …

Cardiovascular disease (CVD) continues to be the primary cause of global mortality.
Vascular smooth muscle cells (VSMCs) are integral components of vascular structure and …

Arterial Vascular smooth muscle cells (VSMCs) play a central role in the onset and
progression of atherosclerosis. Upon exposure to pathological stimuli, they can take on …

This review aimed to trace the inflammatory pathway from the NLRP3 inflammasome to
monomeric C-reactive protein (mCRP) in atherosclerotic cardiovascular disease. CRP is the …