[HTML][HTML] The cell origins of foam cell and lipid metabolism regulated by mechanical stress in atherosclerosis

Z Ouyang, J Zhong, J Shen, Y Zeng - Frontiers in Physiology, 2023 - frontiersin.org
Atherosclerosis is an inflammatory disease initiated by endothelial activation, in which
lipoprotein, cholesterol, extracellular matrix, and various types of immune and non-immune …

[HTML][HTML] Protective interaction of human phagocytic APC subsets with Cryptococcus neoformans induces genes associated with metabolism and antigen presentation

BN Nelson, CS Daugherty, RR Sharp… - Frontiers in …, 2022 - frontiersin.org
Cryptococcal meningitis is the most common cause of meningitis among HIV/AIDS patients
in sub-Saharan Africa, and worldwide causes over 223,000 cases leading to more than …

[HTML][HTML] Mitochondrial and metabolic features of salugenesis and the healing cycle

RK Naviaux - Mitochondrion, 2023 - Elsevier
Pathogenesis and salugenesis are the first and second stages of the two-stage problem of
disease production and health recovery. Salugenesis is the automatic, evolutionarily …

[HTML][HTML] Macrophage-, dendritic-, smooth muscle-, endothelium-, and stem cells-derived foam cells in atherosclerosis

M Kloc, JZ Kubiak, RM Ghobrial - International Journal of Molecular …, 2022 - mdpi.com
Atherosclerosis is an inflammatory disease depending on the buildup, called plaque, of
lipoproteins, cholesterol, extracellular matrix elements, and various types of immune and …

[HTML][HTML] Cholesterol metabolism in the regulation of inflammatory responses

R Bauer, B Brüne, T Schmid - Frontiers in Pharmacology, 2023 - frontiersin.org
The importance of biologically active lipid mediators, such as prostanoids, leukotrienes, and
specialized pro-resolving mediators, in the regulation of inflammation is well established …

MR Imaging of Carotid Artery Atherosclerosis: Updated Evidence on High-Risk Plaque Features and Emerging Trends

JC Benson, L Saba, G Bathla… - American Journal …, 2023 - Am Soc Neuroradiology
MR imaging is well-established as the criterion standard for carotid artery atherosclerosis
imaging. The capability of MR imaging to differentiate numerous plaque components has …

[HTML][HTML] Hydroxytyrosol Reduces Foam Cell Formation and Endothelial Inflammation Regulating the PPARγ/LXRα/ABCA1 Pathway

S Franceschelli, F De Cecco, M Pesce, P Ripari… - International journal of …, 2023 - mdpi.com
Cholesterol accumulation in macrophages leads to the formation of foam cells and
increases the risk of developing atherosclerosis. We have verified whether hydroxytyrosol …

[HTML][HTML] Monocyte and macrophage foam cells in diabetes-accelerated atherosclerosis

J Cervantes, JE Kanter - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Diabetes results in an increased risk of atherosclerotic cardiovascular disease. This
minireview will discuss whether monocyte and macrophage lipid loading contribute to this …

[HTML][HTML] VXX-401, a novel anti-PCSK9 vaccine, reduces LDL-C in cynomolgus monkeys

MM Vroom, H Lu, M Lewis, BA Thibodeaux… - Journal of Lipid …, 2024 - ASBMB
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of disease
burden in the world and is highly correlated with chronic elevations of low-density …

[HTML][HTML] Free radicals and obesity-related chronic inflammation contrasted by antioxidants: A new perspective in coronary artery disease

C Caiati, A Stanca, ME Lepera - Metabolites, 2023 - mdpi.com
We are surrounded by factors called free radicals (FR), which attach to the molecules our
body is made of, first among them the endothelium. Even though FR are to a certain extent a …