The discovery of new immune-modulating biomaterials is of significant value to immuno-
engineering and therapy development. Here, we discovered that single-tailed heterocyclic …

To provide a theoretical basis for the prevention and treatment of atherosclerosis (As), the
current study aimed to investigate the mechanism underlying the effect of homocysteine …

Atherosclerosis is a persistent inflammatory state that contributes significantly to
cardiovascular disease, a primary cause of mortality worldwide. Enhanced lipid uptake by …

ATP-binding cassette transporter A1 (ABCA1) plays a crucial role in atherosclerotic
formation through mediated cholesterol efflux in macrophage-derived foam cells. In this …

Inflammation control is becoming a critical strategy for atherosclerosis management,
because inflammation is involved in plaque progression. In this regard, a biomimetic …

While environmental factors have been considered contributors to atherosclerosis, it
remains unclear whether drinking water promotes foam cell formation, the initial event of …

Cardiovascular diseases (CVDs) are the leading cause of death worldwide. CVDs are
promoted by the accumulation of lipids and immune cells in the endothelial space resulting …

Abstract Interferon Gamma Inducible Protein 16 (IFI16) belongs to the HIN-200 protein family
and is pivotal in immunological responses. Serving as a DNA sensor, IFI16 identifies viral …

Aims: Acute rupture or erosion of unstable atherosclerotic plaques is a major cause of
adverse consequences of atherosclerotic cardiovascular disease, often leading to …

The objective of this study was to investigate the effects of serum amyloid 1 (SAA1) on
activation of endothelial cells, formation of foam cells, platelet aggregation, and …