IRF9 and STAT1 as biomarkers involved in T-cell immunity in atherosclerosis

W Xie, X Gao, L Zhao, S Song, N Li, J Liu - Journal of Biosciences, 2024 - Springer
Atherosclerosis is a common cardiovascular disease in which the arteries are thickened due
to buildup of plaque. This study aims to identify programmed cell death (PCD)-related …

KLF15 transcriptionally activates ATG14 to promote autophagy and attenuate damage of ox-LDL-induced HAECs

D Han, M Huang, Z Chang, W Sun - Molecular Biotechnology, 2024 - Springer
Abstract Kruppel-like factor 15 (KLF15) is involved in many cardiovascular diseases and is
abnormally expressed in atherosclerosis (AS), but the regulatory mechanism of KLF15 in AS …

Comparison of THP-1 Macrophages Viability in Different Types of Culture Vessel: Comparison of Thp-1 Macrophages Viability in Different Types of Culture Vessel

ZNM Yasin, FNM Idrus, GB Yvonne-Tee - Journal of Tropical Life …, 2023 - jtrolis.ub.ac.id
The ox-LDL generated apoptotic bodies using THP-1 macrophage is a useful tool to study
foam cell formation in atherosclerosis. However, the common problem is the cells in the …

P53 in Vascular Remodeling: The Potential for Targeting in Atherosclerosis

AV Poznyak, EB Zhigmitova, VN Sukhorukov… - Journal of Medical and …, 2023 - Springer
Purpose At first, p53 was believed to be present primarily in malignant cells. In fact, p53
turned out to play a major role in vascular remodeling associated with transplantation …

[HTML][HTML] Modification of lipoprotein metabolism and function driving atherogenesis in diabetes

L Luciani, M Pedrelli, P Parini - Atherosclerosis, 2024 - Elsevier
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease, characterized by raised
blood glucose levels and impaired lipid metabolism resulting from insulin resistance and …

[HTML][HTML] PCSK9 抑制剂在颈动脉狭窄中的应用进展

刘鑫, 刘佳 - Advances in Clinical Medicine, 2023 - hanspub.org
颈动脉狭窄(Carotid Artery Stenosis, CAS) 是急性缺血性脑卒中(Ischemic Stroke, IS)
的原因之一, 其主要原因是动脉粥样硬化(Atherosclerosis, AS). 低密度脂蛋白胆固醇(Low …

Integrative Multi-Omics Analysis of IFNγ-induced Macrophages and Atherosclerotic Plaques Reveals Macrophage-dependent STAT1-Driven Transcription in …

M Eskandarian Boroujeni, N Lopacinska, A Antonczyk… - bioRxiv, 2024 - biorxiv.org
This study investigates the role of STAT1-mediated IFNγ signaling in atherosclerosis
progression through multi-omics integration and analysis of human and mouse models of …

[PDF][PDF] Calcified carotid artery atheroma on standard dental panoramic radiographs in a dental school population: a retrospective study

A Taneja - 2023 - open.library.ubc.ca
Objectives: We aimed to determine the prevalence of CCAA detected on DPR's of
individuals over 30 years of age. We assessed if student dentists were able to identify CCAA …

Elucidation of the role of methylarginine metabolism in regulation of nitric oxide production and inflammation

NA Alshuwayer - 2024 - theses.gla.ac.uk
Atherosclerosis is a major global health issue, and inflammation is important in its
pathogenesis. Many atherosclerosis risk factors lead to reduced nitric oxide (NO) …

Targeting Fatty Acid Synthase Reduces Aortic Atherosclerosis and Inflammation

R Meade, C Engel, L Belaygorod, B Arif, FF Hsu… - 2024 - researchsquare.com
Fatty acid synthase (FAS) is predominantly expressed in the liver and adipose tissue. It plays
vital roles in de novo synthesis of saturated fatty acid and regulates insulin sensitivity. We …