Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

Aging of the vasculature plays a central role in morbidity and mortality of older people. To
develop novel treatments for amelioration of unsuccessful vascular aging and prevention of …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated clinical
syndrome COVID-19 are causing overwhelming morbidity and mortality around the globe …

Hypertension affects two-thirds of people aged> 60 years and significantly increases the risk
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …

Hypertension affects a significant proportion of the adult and aging population and
represents an important risk factor for vascular cognitive impairment and late-life dementia …

Importance Low-dose aspirin has been widely used for primary and secondary prevention of
stroke. The balance between potential reduction of ischemic stroke events and increased …

Cognitive impairment, and dementia, are major contributors to global burden of death and
disability, with projected increases in prevalence in all regions of the world, but most marked …

Cerebral small vessel disease (cSVD) is the most common cause of vascular cognitive
impairment and affects all levels of the brain's vasculature. Features include diverse …

Aging-induced structural and functional alterations of the neurovascular unit lead to
impairment of neurovascular coupling responses, dysregulation of cerebral blood flow, and …

Cognitive impairment and dementia are major medical, social, and economic public health
issues worldwide with significant implications for life quality in older adults. The leading …