Cerebral venous congestion exacerbates cerebral microhemorrhages in mice
Abstract Cerebral microhemorrhages (CMHs; microbleeds), which are small focal
intracerebral hemorrhages, importantly contribute to the pathogenesis of cognitive decline …
intracerebral hemorrhages, importantly contribute to the pathogenesis of cognitive decline …
[HTML][HTML] Analysis of cerebrovascular dysfunction caused by chronic social defeat in mice
ML Lehmann, CN Poffenberger, AG Elkahloun… - Brain, behavior, and …, 2020 - Elsevier
Psychological stress and affective disorders are clinically associated with hypertension and
vascular disease, but the biological links between the conditions have not been fully …
vascular disease, but the biological links between the conditions have not been fully …
Six genetically linked mutations in the CD36 gene significantly delay the onset of Alzheimer's disease
O Šerý, T Zeman, K Sheardová, M Vyhnálek… - Scientific Reports, 2022 - nature.com
The risk of Alzheimer's disease (AD) has a strong genetic component, also in the case of late-
onset AD (LOAD). Attempts to sequence whole genome in large populations of subjects …
onset AD (LOAD). Attempts to sequence whole genome in large populations of subjects …
Traumatic brain injury-induced cerebral microbleeds in the elderly
L Toth, A Czigler, P Horvath, B Kornyei, N Szarka… - Geroscience, 2021 - Springer
Traumatic brain injury (TBI) was shown to lead to the development of cerebral microbleeds
(CMBs), which are associated with long term cognitive decline and gait disturbances in …
(CMBs), which are associated with long term cognitive decline and gait disturbances in …
Cerebral microbleeds: beyond the macroscope
M Pétrault, B Casolla, T Ouk… - … Journal of Stroke, 2019 - journals.sagepub.com
While being increasingly recognized in clinical routine, brain microbleeds remain a puzzling
finding for physicians. These small dot-like lesions are thought to be old perivascular …
finding for physicians. These small dot-like lesions are thought to be old perivascular …
Young blood-mediated cerebromicrovascular rejuvenation through heterochronic parabiosis: enhancing blood-brain barrier integrity and capillarization in the aged …
Age-related cerebromicrovascular changes, including blood-brain barrier (BBB) disruption
and microvascular rarefaction, play a significant role in the development of vascular …
and microvascular rarefaction, play a significant role in the development of vascular …
Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice
Clinical and experimental studies show that hypertension induces intracerebral
hemorrhages (ICH), including cerebral microhemorrhages in the aged brain, which …
hemorrhages (ICH), including cerebral microhemorrhages in the aged brain, which …
The Spectrum of Cerebral Small Vessel Disease: Emerging Pathophysiologic Constructs and Management Strategies
Cerebral small vessel disease (CSVD) results in a spectrum of neurologic, behavioral, and
cognitive sequelae, most commonly from white matter hyperintensities (WMH) of presumed …
cognitive sequelae, most commonly from white matter hyperintensities (WMH) of presumed …
Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy …
Abstract Cerebral microhemorrhages (CMHs, microbleeds), a manifestation of age-related
cerebral small vessel disease, contribute to the pathogenesis of cognitive decline and …
cerebral small vessel disease, contribute to the pathogenesis of cognitive decline and …
Increased pulse wave velocity is related to impaired working memory and executive function in older adults with metabolic syndrome
J Gosalia, PS Montgomery, S Zhang, WA Pomilla… - Geroscience, 2022 - Springer
Age-related vascular alterations promote the pathogenesis of vascular cognitive impairment
(VCI). Cardiovascular risk factors that accelerate vascular aging exacerbate VCI. Metabolic …
(VCI). Cardiovascular risk factors that accelerate vascular aging exacerbate VCI. Metabolic …