Cerebral Microbleeds Associate with Brain Endothelial Cell Activation-Dysfunction and Blood–Brain Barrier Dysfunction/Disruption with Increased Risk of …

MR Hayden - Biomedicines, 2024 - mdpi.com
Globally, cerebral microbleeds (CMBs) are increasingly being viewed not only as a marker
for cerebral small vessel disease (SVD) but also as having an increased risk for the …

Sex differences in cognitive impairment induced by cerebral microhemorrhage

R Barus, S Bergeron, F Auger, C Laloux… - Translational Stroke …, 2021 - Springer
It has been suggested that cerebral microhemorrhages (CMHs) could be involved in
cognitive decline. However, little is known about the sex-dependency of this effect. Using a …

Interthalamic adhesion size in aging dogs with presumptive spontaneous brain microhemorrhages: a comparative retrospective MRI study of dogs with and without …

CW Dewey, M Rishniw, PJ Johnson, ES Davies… - PeerJ, 2020 - peerj.com
Objective Spontaneous brain microhemorrhages in elderly people are present to some
degree in Alzheimer's disease patients but have been linked to brain atrophy in the absence …

Linking peripheral atherosclerosis to blood–brain barrier disruption: elucidating its role as a manifestation of cerebral small vessel disease in vascular cognitive …

Á Nyúl-Tóth, R Patai, A Csiszar, A Ungvari, R Gulej… - GeroScience, 2024 - Springer
Aging plays a pivotal role in the pathogenesis of cerebral small vessel disease (CSVD),
contributing to the onset and progression of vascular cognitive impairment and dementia …

Association between insulin resistance, plasma leptin, and neurocognition in vascular cognitive impairment

PJ Smith, S Mabe, A Sherwood… - Journal of …, 2019 - content.iospress.com
Background: Greater body weight has been associated impairments in neurocognition and
greater dementia risk, although the mechanisms linking weight and neurocognition have yet …

Enhanced cerebral microbleeds by long-term air pollution exposure in spontaneously hypertensive rats

L Cai, J Yang, E Cosky, R Xin, X Geng… - Neurological …, 2022 - Taylor & Francis
ABSTRACT Background Cerebral microbleeds (CMBs) are associated with a high risk for
stroke. The present study determined whether long-term exposure to PM2. 5 results in …

Impact of total cerebral small vessel disease score on ophthalmic artery morphologies and hemodynamics

J Wang, X Cheng, Z Meng, Y Wang - Journal of Translational Medicine, 2023 - Springer
Background Cerebral small vessel disease (CSVD) is a systemic disease, affecting not only
the brain, but also eyes and other organs. The total CSVD score is a tool for comprehensive …

Multiple hypointense vessels are associated with cognitive impairment in patients with single subcortical infarction

T Yang, P Peng, S Jiang, Y Yan, Y Hu, H Wang… - Translational Stroke …, 2023 - Springer
We aimed to explore the relationship between multiple hypointense vessels and cognitive
function in patients with single subcortical infarction (SSI) and the role of SSI with different …

Role of cortical microbleeds in cognitive impairment: In vivo behavioral and imaging characterization of a novel murine model

S Bergeron, Y Chen, F Auger, J Deguil… - Journal of Cerebral …, 2019 - journals.sagepub.com
Cerebral microbleeds (CMBs) could contribute to cognitive impairment in the general
population and in patients with dementia. We designed a study to (i) develop a murine …

Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages

A Csiszar, A Ungvari, R Patai, R Gulej… - GeroScience, 2024 - Springer
Cerebral microhemorrhages (CMHs, also known as cerebral microbleeds) are a critical but
frequently underestimated aspect of cerebral small vessel disease (CSVD), bearing …