Role of insulin resistance in human disease

GM Reaven - Diabetes, 1988 - Am Diabetes Assoc
Resistance to insulin-stimulated glucose uptake is present in the majority of patients with
impaired glucose tolerance (IGT) or non-insulin-dependent diabetes mellitus (NIDDM) and …

The long and winding road to optimal HbA1c measurement

RR Little, CL Rohlfing - Clinica chimica acta, 2013 - Elsevier
The importance of hemoglobin A1c (HbA1c) as an indicator of mean glycemia and risks for
complications in patients with diabetes mellitus was established by the results of long-term …

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

DB Sacks, M Arnold, GL Bakris, DE Bruns… - Clinical …, 2011 - academic.oup.com
BACKGROUND Multiple laboratory tests are used to diagnose and manage patients with
diabetes mellitus. The quality of the scientific evidence supporting the use of these tests …

The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population‐based cohort: the Rochester Diabetic …

PJ Dyck, KM Kratz, JL Karnes, WJ Litchy, R Klein… - Neurology, 1993 - AAN Enterprises
The magnitude of the health problem from diabetic neuropathies remains inadequately
estimated due to the lack of prospective population-based studies employing standardized …

Management of newly diagnosed type 2 diabetes mellitus (T2DM) in children and adolescents

KC Copeland, J Silverstein, KR Moore, GE Prazar… - …, 2013 - publications.aap.org
Over the past 3 decades, the prevalence of childhood obesity has increased dramatically in
North America, ushering in a variety of health problems, including type 2 diabetes mellitus …

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

DB Sacks, DE Bruns, DE Goldstein… - Clinical …, 2002 - academic.oup.com
Background: Multiple laboratory tests are used in the diagnosis and management of patients
with diabetes mellitus. The quality of the scientific evidence supporting the use of these …

Risk factors for severity of diabetic polyneuropathy: intensive longitudinal assessment of the Rochester Diabetic Neuropathy Study cohort.

PJ Dyck, JL Davies, DM Wilson, FJ Service… - Diabetes …, 1999 - Am Diabetes Assoc
OBJECTIVE: Chronic hyperglycemia relates to the occurrence of diabetic polyneuropathy
(DPN), but has not yet been shown to relate to its overall severity In addition, the degree and …

Measurement of hemoglobin A1c by a new liquid-chromatographic assay: methodology, clinical utility, and relation to glucose tolerance evaluated.

JO Jeppsson, P Jerntorp, G Sundkvist… - Clinical …, 1986 - academic.oup.com
A chromatographic method for determining glycated hemoglobin (Hb A1c) by use of a new
monodisperse cation-exchanger has been investigated. Hb A1c was separated from other" …

Changes in insulin and lipid metabolism in males with asymptomatic hyperuricaemia

I Zavaroni, S Mazza, M Fantuzzi… - Journal of internal …, 1993 - Wiley Online Library
Objectives. To define the effect of asymptomatic hyperuricaemia on various facets of
glucose, insulin, and lipoprotein metabolism. Design. Case control study in health …

Long-term safety, efficacy and side-effects of continuous subcutaneous insulin infusion treatment for type 1 (insulin-dependent) diabetes mellitus: a one centre …

E Chantelau, M Spraul, I Mühlhauser, R Gause… - Diabetologia, 1989 - Springer
A follow-up study of 116 Type 1 (insulin-dependent) diabetic patients on long-term
continuous subcutaneous insulin infusion was conducted after 4.5±0.2 years. The average …