Abstract PI3K/AKT/mTOR pathway is one of the most important signaling pathways involved
in normal cellular processes. Its aberrant activation modulates autophagy, epithelial …

Simple Summary The advancement of nanotechnology over the last three decades has
given new hope to cancer management. The first FDA-approved nanomedicine (DOXIL) was …

Cancer has long been regarded as one of the world's most fatal diseases, claiming the lives
of countless individuals each year. Stomach cancer is a prevalent cancer that has recently …

Autophagy modulation is considered to be a promising programmed cell death mechanism
to prevent and cure a great number of disorders and diseases. The crucial step in designing …

Background Tumor recurrence and metastasis occur at a high rate in patients with colon
cancer. Identification of effective strategies for the treatment of colon cancer is critical …

Gastric cancer represents a deadly malignancy worldwide, yet current therapeutic regimens
remain ineffective. Nanoparticle (NP)-based solutions could allow the design of novel …

Upper gastrointestinal (GI) carcinomas are characterized as one of the deadliest cancer
types with the highest recurrence rates. Their treatment is challenging due to late diagnosis …

With the development of materials science and biomedicine, the application of
nanomaterials in the medical field is further promoted. In the process of the diagnosis and …

Despite advances by recently approved antibody‐drug conjugates in treating advanced
gastric cancer patients, substantial limitations remain. Here, several key obstacles are …

Osteosarcoma (OS) is one of the most common primary bone malignancies in children and
adolescents. The toxicity to healthy tissues from conventional therapeutic strategies …