[HTML][HTML] Advances in aptamer-based biomarker discovery

J Huang, X Chen, X Fu, Z Li, Y Huang… - Frontiers in Cell and …, 2021 - frontiersin.org
The discovery and identification of biomarkers promote the rational and fast development of
medical diagnosis and therapeutics. Clinically, the application of ideal biomarkers still is …

[HTML][HTML] Is there a maternal blood biomarker that can predict spontaneous preterm birth prior to labour onset? A systematic review

KK Hornaday, EM Wood, DM Slater - PloS one, 2022 - journals.plos.org
Introduction The ability to predict spontaneous preterm birth (sPTB) prior to labour onset is a
challenge, and it is currently unclear which biomarker (s), may be potentially predictive of …

[HTML][HTML] The prediction of early preeclampsia: Results from a longitudinal proteomics study

AL Tarca, R Romero, N Benshalom-Tirosh, NG Than… - PloS one, 2019 - journals.plos.org
Objectives To identify maternal plasma protein markers for early preeclampsia (delivery< 34
weeks of gestation) and to determine whether the prediction performance is affected by …

Complement activation, a threat to pregnancy

G Girardi - Seminars in immunopathology, 2018 - Springer
Pregnancy poses a challenge for the immune systems of placental mammals. As fetal
tissues are semi-allogeneic and alloantibodies that commonly develop in the mother, the …

[HTML][HTML] Human placental proteomics and exon variant studies link AAT/SERPINA1 with spontaneous preterm birth

H Tiensuu, AM Haapalainen, P Tissarinen, A Pasanen… - BMC medicine, 2022 - Springer
Background Preterm birth is defined as live birth before 37 completed weeks of pregnancy,
and it is a major problem worldwide. The molecular mechanisms that lead to onset of …

The maternal plasma proteome changes as a function of gestational age in normal pregnancy: a longitudinal study

R Romero, O Erez, E Maymon… - American journal of …, 2017 - Elsevier
Objective Pregnancy is accompanied by dramatic physiological changes in maternal plasma
proteins. Characterization of the maternal plasma proteome in normal pregnancy is an …

Early angiogenic proteins associated with high risk for bronchopulmonary dysplasia and pulmonary hypertension in preterm infants

S Arjaans, BD Wagner, PM Mourani… - … of Physiology-Lung …, 2020 - journals.physiology.org
Early pulmonary vascular disease in preterm infants is associated with the subsequent
development of bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH); …

[HTML][HTML] Plasma biomarkers of reticular pseudodrusen and the risk of progression to advanced age-related macular degeneration

AM Lynch, BD Wagner, AG Palestine… - … vision science & …, 2020 - tvst.arvojournals.org
Purpose: To determine, using an aptamer-based technology in patients with intermediate
age-related macular degeneration (AMD),(1) if there is a difference in plasma levels of 4979 …

Proteomic analysis of first trimester maternal serum to identify candidate biomarkers potentially predictive of spontaneous preterm birth

AM D'Silva, JA Hyett, JR Coorssen - Journal of proteomics, 2018 - Elsevier
Spontaneous preterm birth (sPTB) remains a major clinical dilemma; current diagnostics and
interventions have not reduced the rate of this serious healthcare burden. This study …

[HTML][HTML] Identifying potential biomarkers related to pre-term delivery by proteomic analysis of amniotic fluid

S Hong, JE Lee, YM Kim, Y Park, JW Choi, KH Park - Scientific Reports, 2020 - nature.com
We sought to identify biomarkers in the amniotic fluid (AF) and specific signaling pathways
related to spontaneous preterm delivery (SPTD,< 34 weeks) in women with preterm labor …