[HTML][HTML] Cannabidiol (CBD) as a promising anti-cancer drug

ES Seltzer, AK Watters, D MacKenzie, LM Granat… - Cancers, 2020 - mdpi.com
Recently, cannabinoids, such as cannabidiol (CBD) and Δ 9-tetrahydrocannabinol (THC),
have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a …

[HTML][HTML] Cannabinoids as anticancer drugs: current status of preclinical research

B Hinz, R Ramer - British journal of cancer, 2022 - nature.com
Drugs that target the endocannabinoid system are of interest as pharmacological options to
combat cancer and to improve the life quality of cancer patients. From this perspective …

An update on safety and side effects of cannabidiol: a review of clinical data and relevant animal studies

K Iffland, F Grotenhermen - Cannabis and cannabinoid research, 2017 - liebertpub.com
Introduction: This literature survey aims to extend the comprehensive survey performed by
Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from …

Cannabidiol: State of the art and new challenges for therapeutic applications

S Pisanti, AM Malfitano, E Ciaglia, A Lamberti… - Pharmacology & …, 2017 - Elsevier
Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …

[HTML][HTML] Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis

AM Tomko, EG Whynot, LD Ellis, DJ Dupré - Cancers, 2020 - mdpi.com
In recent years, and even more since its legalization in several jurisdictions, cannabis and
the endocannabinoid system have received an increasing amount of interest related to their …

Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

[HTML][HTML] The endocannabinoid system: A target for cancer treatment

C Laezza, C Pagano, G Navarra, O Pastorino… - International journal of …, 2020 - mdpi.com
In recent years, the endocannabinoid system has received great interest as a potential
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …

Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol

P Alves, C Amaral, N Teixeira… - Pharmacological …, 2020 - Elsevier
Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …

[HTML][HTML] Cannabinoids in glioblastoma therapy: new applications for old drugs

CA Dumitru, IE Sandalcioglu, M Karsak - Frontiers in molecular …, 2018 - frontiersin.org
Glioblastoma (GBM) is the most malignant brain tumor and one of the deadliest types of
solid cancer overall. Despite aggressive therapeutic approaches consisting of maximum …

Emerging potential of cannabidiol in reversing proteinopathies

R Dash, MC Ali, I Jahan, YA Munni, S Mitra… - Ageing research …, 2021 - Elsevier
The aberrant accumulation of disease-specific protein aggregates accompanying cognitive
decline is a pathological hallmark of age-associated neurological disorders, also termed as …