Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

The morbidity and mortality of autoimmune diseases (Ads) have been increasing worldwide,
and the identification of novel therapeutic strategies for prevention and treatment is urgently …

Diabetic kidney disease is known as a major cause of chronic kidney disease and end stage
renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are …

MicroRNAs (miRNAs) play a critical role in regulating various biological processes, such as
cell differentiation and immune modulation by binding to their target genes. miR-223 is a …

Rheumatoid arthritis (RA) is an autoimmune disease involving joints, with clinical
manifestations of joint inflammation, bone damage and cartilage destruction, joint …

Aging is characterized by progressive functional deterioration with increased risk of
mortality. It is a complex biological process driven by a multitude of intertwined mechanisms …

Ethnopharmacological relevance Herba taxilli (HT, Sangjisheng in Chinese), which is
composed of the dried stems and leaves of Taxillus chinensis (DC.) Danser, has been …

The present study was designed to explore the biological role of resveratrol (RES) in
rheumatoid arthritis (RA) and the underlying mechanism. The adjuvant‐induced arthritic rats …

Objective Cantleyoside (CA) is a kind of iridoid glycosides in Pterocephalus hookeri (CB
Clarke) Höeck. The purpose of this study was to investigate the effects of CA on human …

In recent years, epigenetic modifications have been widely researched. As humans age,
environmental and genetic factors may drive inflammation and immune responses by …