A guide to the composition and functions of the extracellular matrix
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …
provides structural support for the cells and tissues. Accumulated knowledge clearly …
[PDF][PDF] The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia
As the principal tissue for insulin-stimulated glucose disposal, skeletal muscle is a primary
driver of whole-body glycemic control. Skeletal muscle also uniquely responds to muscle …
driver of whole-body glycemic control. Skeletal muscle also uniquely responds to muscle …
Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function
Understanding gene function and regulation in homeostasis and disease requires
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …
Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions
MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …
been extensively researched since the landmark report by Morpurgo (1897) of “work …
Adult stem cell niches for tissue homeostasis
Adult stem cells are fundamental to maintain tissue homeostasis, growth, and regeneration.
They reside in specialized environments called niches. Following activating signals, they …
They reside in specialized environments called niches. Following activating signals, they …
Skeletal muscle differentiation of human iPSCs meets bioengineering strategies: perspectives and challenges
Although skeletal muscle repairs itself following small injuries, genetic diseases or severe
damages may hamper its ability to do so. Induced pluripotent stem cells (iPSCs) can …
damages may hamper its ability to do so. Induced pluripotent stem cells (iPSCs) can …
[HTML][HTML] The role of the skeletal muscle secretome in mediating endurance and resistance training adaptations
Exercise, in the form of endurance or resistance training, leads to specific molecular and
cellular adaptions not only in skeletal muscles, but also in many other organs such as the …
cellular adaptions not only in skeletal muscles, but also in many other organs such as the …
A glitch in the matrix: the pivotal role for extracellular matrix remodeling during muscle hypertrophy
CR Brightwell, CM Latham… - … of Physiology-Cell …, 2022 - journals.physiology.org
Multinuclear muscle fibers are the most voluminous cells in skeletal muscle and the primary
drivers of growth in response to loading. Outside the muscle fiber, however, is a diversity of …
drivers of growth in response to loading. Outside the muscle fiber, however, is a diversity of …
A review of recent advances in natural polymer-based scaffolds for musculoskeletal tissue engineering
The musculoskeletal (MS) system consists of bone, cartilage, tendon, ligament, and skeletal
muscle, which forms the basic framework of the human body. This system plays a vital role in …
muscle, which forms the basic framework of the human body. This system plays a vital role in …
Tissue-specific parameters for the design of ECM-mimetic biomaterials
The extracellular matrix (ECM) is a complex network of biomolecules that mechanically and
biochemically directs cell behavior and is crucial for maintaining tissue function and health …
biochemically directs cell behavior and is crucial for maintaining tissue function and health …