Rise and fall of Caspofungin: the current status of Caspofungin as a treatment for Cryptococcus neoformans infection

TKB Aguiar, ACM Costa, NAS Neto, DMS Brito… - Future …, 2024 - Taylor & Francis
Antifungal infections are becoming a major concern to human health due to antimicrobial
resistance. Echinocandins have been promising agents against resistant fungal infections …

Temporal trends in antifungal susceptibility of Cryptococcus neoformans isolates from a reference laboratory in the United States, 2011–2021

EE Ordaya, OM Abu Saleh, P Vergidis, SM Deml… - Mycoses, 2024 - Wiley Online Library
Background There are no established clinical breakpoints for antifungal agents against
Cryptococcus species; however, epidemiological cut‐off values can help distinguish wild …

Genotypic diversity and antifungal susceptibility of Cryptococcus neoformans species complex from China, including the diploid VNIII isolates from HIV-infected …

L Zhang, S Wang, N Hong, M Li, Y Liu, T Zhou… - Medical …, 2023 - academic.oup.com
Although previous studies on the genotypic diversity and antifungal susceptibility of the
Cryptococcus neoformans species complex (CNSC) isolates from China revealed ST5 …

Reduced Susceptibility to Azoles in Cryptococcus gattii Correlates with the Substitution R258L in a Substrate Recognition Site of the Lanosterol 14-α-Demethylase

SK Carvajal, J Melendres, P Escandón… - Microbiology …, 2023 - Am Soc Microbiol
Cryptococcus neoformans and Cryptococcus gattii cause cryptococcosis, a life-threatening
fungal infection affecting mostly immunocompromised patients. In fact, cryptococcal …

Deep mutational scanning to study the role of epistasis in antifungal resistance.

EMM Alexander - 2023 - corpus.ulaval.ca
Résumé Dans le domaine de la résistance aux antifongiques, il est important de
comprendre la dynamique entre l'épistasie et les trajectoires évolutives afin de pouvoir …