[PDF][PDF] Epigenetic regulation of early human embryo development
AL Wilkinson, I Zorzan, PJ Rugg-Gunn - Cell Stem Cell, 2023 - cell.com
Studies of mammalian development have advanced our understanding of the genetic,
epigenetic, and cellular processes that orchestrate embryogenesis and have uncovered …
epigenetic, and cellular processes that orchestrate embryogenesis and have uncovered …
A new era of stem cell and developmental biology: from blastoids to synthetic embryos and beyond
Y Kim, I Kim, K Shin - Experimental & Molecular Medicine, 2023 - nature.com
Recent discoveries in stem cell and developmental biology have introduced a new era
marked by the generation of in vitro models that recapitulate early mammalian development …
marked by the generation of in vitro models that recapitulate early mammalian development …
[HTML][HTML] Modelling post-implantation human development to yolk sac blood emergence
Implantation of the human embryo begins a critical developmental stage that comprises
profound events including axis formation, gastrulation and the emergence of haematopoietic …
profound events including axis formation, gastrulation and the emergence of haematopoietic …
Reprogrammed blastoids contain amnion-like cells but not trophectoderm
C Zhao, AP Reyes, JP Schell, J Weltner, N M. Ortega… - biorxiv, 2021 - biorxiv.org
With the advancement of human stem cell cultures and interest in understanding human
embryogenesis, human blastocyst-like structures, or human blastoids, are being developed …
embryogenesis, human blastocyst-like structures, or human blastoids, are being developed …
Hypoblast from human pluripotent stem cells regulates epiblast development
T Okubo, N Rivron, M Kabata, H Masaki, K Kishimoto… - Nature, 2024 - nature.com
Recently, several studies using cultures of human embryos together with single-cell RNA-
seq analyses have revealed differences between humans and mice, necessitating the study …
seq analyses have revealed differences between humans and mice, necessitating the study …
[PDF][PDF] The emergence of human gastrulation upon in vitro attachment
R De Santis, E Rice, G Croft, M Yang… - Stem Cell Reports, 2024 - cell.com
While studied extensively in model systems, human gastrulation remains obscure. The
scarcity of fetal biological material as well as ethical considerations limit our understanding …
scarcity of fetal biological material as well as ethical considerations limit our understanding …
VGLL1 cooperates with TEAD4 to control human trophectoderm lineage specification
Y Yang, W Jia, Z Luo, Y Li, H Liu, L Fu, J Li… - Nature …, 2024 - nature.com
In contrast to rodents, the mechanisms underlying human trophectoderm and early placenta
specification are understudied due to ethical barriers and the scarcity of embryos. Recent …
specification are understudied due to ethical barriers and the scarcity of embryos. Recent …
Stem cells used to model a two-week-old human embryo
N Moris - 2023 - nature.com
Stem cells used to model a two-week-old human embryo Skip to main content Thank you for
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3D reconstruction of a gastrulating human embryo
Z Xiao, L Cui, Y Yuan, N He, X Xie, S Lin, X Yang… - Cell, 2024 - cell.com
Progress in understanding early human development has been impeded by the scarcity of
reference datasets from natural embryos, particularly those with spatial information during …
reference datasets from natural embryos, particularly those with spatial information during …
How developmental cell atlases inform stem cell embryo models
How developmental cell atlases inform stem cell embryo models | Nature Methods Skip to main
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