Intracellular lifestyle of Chlamydia trachomatis and host–pathogen interactions

K Stelzner, N Vollmuth, T Rudel - Nature Reviews Microbiology, 2023 - nature.com
In recent years, substantial progress has been made in the understanding of the intracellular
lifestyle of Chlamydia trachomatis and how the bacteria establish themselves in the human …

[HTML][HTML] Intracellular bacteria in cancer—prospects and debates

L Schorr, M Mathies, E Elinav, J Puschhof - npj Biofilms and …, 2023 - nature.com
Recent evidence suggests that some human cancers may harbor low-biomass microbial
ecosystems, spanning bacteria, viruses, and fungi. Bacteria, the most-studied kingdom in …

[HTML][HTML] Potential role of vaginal microbiota in ovarian cancer carcinogenesis, progression and treatment

X Zhao, Z Liu, T Chen - Pharmaceutics, 2023 - mdpi.com
Ovarian cancer represents one of the most challenging gynecologic cancers which still has
numerous unknowns on the underlying pathogenesis. In addition to the verified contributors …

[HTML][HTML] Chlamydial and Gonococcal Genital Infections: A Narrative Review

R Rodrigues, P Vieira-Baptista, C Catalão… - Journal of Personalized …, 2023 - mdpi.com
Sexually transmitted infections (STIs) constitute one of the leading causes of disease burden
worldwide, leading to considerable morbidity, mortality, health expenditures, and stigma. Of …

[HTML][HTML] Chlamydia trachomatis induces disassembly of the primary cilium to promote the intracellular infection

R Ekka, A Gutierrez, KA Johnson, M Tan… - PLoS …, 2024 - journals.plos.org
Chlamydia trachomatis is a clinically important bacterium that infects epithelial cells of the
genitourinary and respiratory tracts and the eye. These differentiated cells are in a quiescent …

Host cell amplification of nutritional stress contributes to persistence in Chlamydia trachomatis

ND Pokorzynski, MR Alla, RA Carabeo - Mbio, 2022 - Am Soc Microbiol
Persistence, a viable but non-replicating growth state, has been implicated in diseases
caused by Chlamydia trachomatis. Starvation of distinct nutrients produces a superficially …

[HTML][HTML] Therapeutic bacteria and viruses to combat cancer: double-edged sword in cancer therapy: new insights for future

A Yarahmadi, M Zare, M Aghayari, H Afkhami… - Cell Communication and …, 2024 - Springer
Cancer, ranked as the second leading cause of mortality worldwide, leads to the death of
approximately seven million people annually, establishing itself as one of the most …

[PDF][PDF] A single-cell landscape of pre-and post-menopausal high-grade serous ovarian cancer ascites

W Chen, H Liu, X Huang, L Qian, L Chen, Y Zhou, Y Liu… - Iscience, 2023 - cell.com
High-grade serous ovarian cancer (HGSOC) is a hormone-related cancer with high mortality
and poor prognosis. Based on the transcriptome of 57,444 cells in ascites from 10 patients …

The microbiome and gynecologic cancer: cellular mechanisms and clinical applications

J Chalif, H Wang, D Spakowicz, A Quick… - International Journal of …, 2024 - ijgc.bmj.com
The microbiome plays a vital function in maintaining human health and homeostasis. Each
microbiota has unique characteristics, including those of the gastrointestinal and female …

Sexually Transmitted Infections and Risk of Epithelial Ovarian Cancer: Results From the Finnish Maternity Cohort

E Skarga, HM Surcel, R Kaaks… - The Journal of …, 2023 - academic.oup.com
Background Sexually transmitted infections, specifically Chlamydia trachomatis (CT), may
be associated with epithelial ovarian cancer (EOC) risk. The association between CT and …