[HTML][HTML] Targeting macrophages in cancer immunotherapy
Z Duan, Y Luo - Signal transduction and targeted therapy, 2021 - nature.com
Immunotherapy is regarded as the most promising treatment for cancers. Various cancer
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …
[HTML][HTML] Targeting tumor-associated macrophages to synergize tumor immunotherapy
X Xiang, J Wang, D Lu, X Xu - Signal transduction and targeted therapy, 2021 - nature.com
The current treatment strategies in advanced malignancies remain limited. Notably,
immunotherapies have raised hope for a successful control of these advanced diseases, but …
immunotherapies have raised hope for a successful control of these advanced diseases, but …
Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function
Understanding gene function and regulation in homeostasis and disease requires
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …
Macrophage-based approaches for cancer immunotherapy
Adoptive cell therapy with genetically modified T cells has generated exciting outcomes in
hematologic malignancies, but its application to solid tumors has proven challenging. This …
hematologic malignancies, but its application to solid tumors has proven challenging. This …
Green tea derivative driven smart hydrogels with desired functions for chronic diabetic wound treatment
X Zhao, D Pei, Y Yang, K Xu, J Yu… - Advanced functional …, 2021 - Wiley Online Library
Current treatments for chronic diabetic wounds remain unsatisfactory due to the lack of ideal
wound dressings that can integrate matching mechanical strength, fast self‐healability, facile …
wound dressings that can integrate matching mechanical strength, fast self‐healability, facile …
The tumor microenvironment innately modulates cancer progression
DC Hinshaw, LA Shevde - Cancer research, 2019 - AACR
Cancer development and progression occurs in concert with alterations in the surrounding
stroma. Cancer cells can functionally sculpt their microenvironment through the secretion of …
stroma. Cancer cells can functionally sculpt their microenvironment through the secretion of …
[PDF][PDF] BCG vaccination in humans elicits trained immunity via the hematopoietic progenitor compartment
B Cirovic, LCJ de Bree, L Groh, BA Blok, J Chan… - Cell host & …, 2020 - cell.com
Induction of trained immunity by Bacille-Calmette-Guérin (BCG) vaccination mediates
beneficial heterologous effects, but the mechanisms underlying its persistence and …
beneficial heterologous effects, but the mechanisms underlying its persistence and …
[HTML][HTML] Hematological methods in fish–Not only for beginners
M Witeska, E Kondera, K Ługowska, B Bojarski - Aquaculture, 2022 - Elsevier
Hematological analyses are commonly used to evaluate fish health and welfare in
aquaculture, veterinary practice and scientific research. Hematological parameters were …
aquaculture, veterinary practice and scientific research. Hematological parameters were …
[HTML][HTML] More than just attractive: how CCL2 influences myeloid cell behavior beyond chemotaxis
M Gschwandtner, R Derler, KS Midwood - Frontiers in immunology, 2019 - frontiersin.org
Monocyte chemoattractant protein-1 (MCP-1/CCL2) is renowned for its ability to drive the
chemotaxis of myeloid and lymphoid cells. It orchestrates the migration of these cell types …
chemotaxis of myeloid and lymphoid cells. It orchestrates the migration of these cell types …
[HTML][HTML] Tumor-associated macrophages: recent insights and therapies
J Zhou, Z Tang, S Gao, C Li, Y Feng, X Zhou - Frontiers in oncology, 2020 - frontiersin.org
Macrophages, which have functions of engulfing and digesting foreign substances, can
clear away harmful matter, including cellular debris and tumor cells. Based on the condition …
clear away harmful matter, including cellular debris and tumor cells. Based on the condition …