Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

Background Multiple blood transcriptional signatures have been proposed for identification
of active and incipient tuberculosis. We aimed to compare the performance of systematically …

Mass spectrometry-based proteomic technique has become indispensable in current
exploration of complex and dynamic biological processes. Instrument development has …

Novel proteomics platforms, such as the aptamer‐based SOMAscan platform, can quantify
large numbers of proteins efficiently and cost‐effectively and are rapidly growing in …

Rapid, accurate, sputum-free tests for tuberculosis (TB) triage and confirmation are urgently
needed to close the widening diagnostic gap. We summarise key technologies and review …

Background Globally, children under 15 years represent approximately 12% of new
tuberculosis cases, but 16% of the estimated 1.4 million deaths. This higher share of …

The ADP ribosyltransferases (PARPs 1–17) regulate diverse cellular processes, including
DNA damage repair. PARPs are classified on the basis of their ability to catalyze poly-ADP …

Tuberculosis (TB), considered an ancient disease, is still killing one person every 21
seconds. Diagnosis of Mycobacterium tuberculosis (M. tb) still has many challenges …

Background Only the tuberculin skin test (TST) and two interferon-γ release assays (IGRAs),
QuantiFERON-TB Gold In-Tube and T-SPOT. TB, are currently endorsed by the World …

Tuberculosis (TB) is the leading killer among all infectious diseases worldwide despite
extensive use of the Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine. A safer …