[HTML][HTML] Amyotrophic lateral sclerosis: an update for 2013 clinical features, pathophysiology, management and therapeutic trials

PH Gordon - Aging and disease, 2013 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS), first described by Jean-Martin Charcot in the 1870s, is
an age-related disorder that leads to degeneration of motor neurons. The disease begins …

[HTML][HTML] Amyotrophic lateral sclerosis (ALS): three letters that change the people's life. For ever

ASB Oliveira, RDB Pereira - Arquivos de neuro-psiquiatria, 2009 - SciELO Brasil
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the motor
nervous system. It causes progressive and cumulative physical disabilities in patients, and …

[HTML][HTML] Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study

ProGas Study Group - The Lancet Neurology, 2015 - Elsevier
Background Gastrostomy feeding is commonly used to support patients with amyotrophic
lateral sclerosis who develop severe dysphagia. Although recommended by both the …

Amyotrophic lateral sclerosis: pathophysiology, diagnosis and management

PH Gordon - CNS drugs, 2011 - Springer
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease associated
with a life expectancy of approximately 3 years after symptom onset, but the range of survival …

Gastrostomy use in motor neurone disease (MND): a review, meta-analysis and survey of current practice

T Stavroulakis, T Walsh, PJ Shaw… - … Lateral Sclerosis and …, 2013 - Taylor & Francis
Gastrostomy feeding is commonly used to support MND patients with dysphagia. In this
paper we review three main methods of gastrostomy insertion (PEG, RIG, PIG); conduct a …

Amyotrophic lateral sclerosis patients' self‐reported satisfaction with assistive technology

KL Gruis, PA Wren, JE Huggins - Muscle & nerve, 2011 - Wiley Online Library
Introduction: Assistive devices are prescribed for amyotrophic lateral sclerosis (ALS) patients
with motor deficits, but little is known about their perceived benefit. Therefore, we assessed …

The impact of gastrostomy in motor neurone disease: challenges and benefits from a patient and carer perspective

T Stavroulakis, WO Baird, SK Baxter… - BMJ Supportive & …, 2016 - spcare.bmj.com
Objectives This study explores the experience of gastrostomy insertion from the perspective
of the patients and their informal carers. Gastrostomy feeding is commonly used to support …

A low molecular weight dextran sulphate, ILB®, for the treatment of amyotrophic lateral sclerosis (ALS): An open-label, single-arm, single-centre, phase II trial

V Srinivasan, V Homer, D Barton, A Clutterbuck-James… - Plos one, 2024 - journals.plos.org
Background Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig´ s disease, is a
rare neurological condition and is the most common motor neurone disease. It is a fatal …

Rehabilitation of motor neuron disease

Z Simmons - Handbook of clinical neurology, 2013 - Elsevier
Amyotrophic lateral sclerosis (ALS), the most common adult motor neuron disease, is an
acquired disorder that results in loss of function in multiple domains. Although there is no …

Multidisciplinary interventions in motor neuron disease

UE Williams, EE Philip-Ephraim… - Journal of …, 2014 - Wiley Online Library
Motor neuron disease is a neurodegenerative disease characterized by loss of upper motor
neuron in the motor cortex and lower motor neurons in the brain stem and spinal cord. Death …