Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

Phylogenies are important for addressing various biological questions such as relationships
among species or genes, the origin and spread of viral infection and the demographic …

The composition of the intestinal microbiome varies considerably between individuals and is
correlated with health. Understanding the extent to which, and how, host genetics …

The past few years have witnessed a revolution in our ability to obtain DNA from ancient
humans. This important new data has added to our knowledge from archaeology and …

Prevotella copri is a common human gut microbe that has been both positively and
negatively associated with host health. In a cross-continent meta-analysis exploiting> 6,500 …

Species can be defined as populations that are diagnosably distinct, reproductively isolated,
cohesive, or exclusive groups of organisms. Boundaries between species in sympatry are …

We present a DNA library preparation method that has allowed us to reconstruct a high-
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …

Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …

There exists an undeniable chasm between the capacities of humans and those of animals.
Our minds have spawned civilizations and technologies that have changed the face of the …

New York Times bestselling author Sam Harris's first book, The End of Faith, ignited a
worldwide debate about the validity of religion. In the aftermath, Harris discovered that most …