Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Biochemistry, safety, pharmacological activities, and clinical applications of turmeric: a mechanistic review

RS Ahmad, MB Hussain, MT Sultan… - Evidence‐Based …, 2020 - Wiley Online Library
Turmeric (Curcuma longa L.) is a popular natural drug, traditionally used for the treatment of
a wide range of diseases. Its root, as its most popular part used for medicinal purposes …

Curcumin, inflammation, and chronic diseases: how are they linked?

Y He, Y Yue, X Zheng, K Zhang, S Chen, Z Du - Molecules, 2015 - mdpi.com
It is extensively verified that continued oxidative stress and oxidative damage may lead to
chronic inflammation, which in turn can mediate most chronic diseases including cancer …

Potential anticancer properties and mechanisms of action of curcumin

NG Vallianou, A Evangelopoulos, N Schizas… - Anticancer …, 2015 - ar.iiarjournals.org
Curcumin, a yellow substance belonging to the polyphenols superfamily, is the active
component of turmeric, a common Indian spice, which is derived from the dried rhizome of …

Polyphenols: benefits to the cardiovascular system in health and in aging

S Khurana, K Venkataraman, A Hollingsworth, M Piche… - Nutrients, 2013 - mdpi.com
Numerous studies have demonstrated the importance of naturally occurring dietary
polyphenols in promoting cardiovascular health and emphasized the significant role these …

[HTML][HTML] Endoplasmic reticulum stress activates unfolded protein response signaling and mediates inflammation, obesity, and cardiac dysfunction: therapeutic and …

OM Amen, SD Sarker, R Ghildyal, A Arya - Frontiers in pharmacology, 2019 - frontiersin.org
Obesity has been implicated as a risk factor for insulin resistance and cardiovascular
diseases (CVDs). Although the association between obesity and CVD is a well-established …

Neuroprotective effect of curcumin against cerebral ischemia-reperfusion via mediating autophagy and inflammation

L Huang, C Chen, X Zhang, X Li, Z Chen… - Journal of Molecular …, 2018 - Springer
Curcumin, a polyphenolic compound extracted from Curcuma longa, has drawn attention for
its effective bioactivities against ischemia-induced injury. This study aimed to evaluate the …

Are curcuminoids effective C‐reactive protein‐lowering agents in clinical practice? Evidence from a meta‐analysis

A Sahebkar - Phytotherapy research, 2014 - Wiley Online Library
Background: Inflammation plays a pivotal role in the pathogenesis of atherosclerosis and
cardiovascular disease (CVD). In this context, C‐reactive protein (CRP) has been identified …

Potential protective roles of curcumin against cadmium-induced toxicity and oxidative stress

JH Park, BM Lee, HS Kim - Journal of Toxicology and …, 2021 - Taylor & Francis
Curcumin, used as a spice and traditional medicine in India, exerts beneficial effects against
several diseases, owing to its antioxidant, analgesic, and anti-inflammatory properties …

Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double …

SA Jazayeri-Tehrani, SM Rezayat, S Mansouri… - Nutrition & …, 2019 - Springer
Background Since lifestyle changes are main therapies for non-alcoholic fatty liver disease
(NAFLD), changing dietary components (nutritional or bioactive) may play a parallel …