[HTML][HTML] Recent advances in chemistry and therapeutic potential of functionalized quinoline motifs–a review

OO Ajani, KT Iyaye, OT Ademosun - RSC advances, 2022 - pubs.rsc.org
Quinoline, which consists of benzene fused with N-heterocyclic pyridine, has received
considerable attention as a core template in drug design because of its broad spectrum of …

Quinoline‐derivatives as privileged scaffolds for medicinal and pharmaceutical chemists: A comprehensive review

V Yadav, J Reang, V Sharma, J Majeed… - Chemical Biology & …, 2022 - Wiley Online Library
The quinoline scaffolds are privileged for their numerous biological activities in the
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …

Deciphering the Mechanism of MRSA Targeting Copper(II) Complexes of NN2 Pincer-Type Ligands

A Das, R Sangavi, S Gowrishankar, R Kumar… - Inorganic …, 2023 - ACS Publications
WHO lists AMR as one of the top ten global public health issues. Therefore, constant effort is
needed to develop more efficient antimicrobial drugs. As a result, earth-abundant transition …

Ring opening ring closure reactions with 5, 9-diethyl-7-(chromon-3-yl)-7-hydroquinolino [3′, 4′: 5, 6] pyrano [3, 2-c] quinoline-6, 8 (5H, 9H)-dione with some 1, 2 …

AS Badran, A Ahmed, AI Nabeel, MA Ibrahim - Journal of Molecular …, 2024 - Elsevier
The chemical behaviour of electron deficient substrate 1 was investigated with some 1, 2-bi-
nucleophilic reagents. Reaction of substrate 1 with hydrazine derivatives namely hydrazine …

Unveiling the crystal structure and quantum properties of 6‑bromo-N-pyridin-4-yl-2-thiophen-2-ylquinoline-4-carboxamide: A promising journey towards predicting its …

TS Shashidhara, CS Navyashree, MK Hema… - Journal of Molecular …, 2023 - Elsevier
The wide range of pharmalogical activity exhibited by quinoline derivatives, due to its fused
benzene ring with pyridine structure, has made them a popular framework for medicinal …

Nucleophilic reactions with the novel 7-(chromon-3-yl) quinolino [3′, 4′: 5, 6] pyrano [3, 2-c] quinoline: Synthesis, biological and computational studies

A Ahmed, MA Ibrahim, AS Badran - Journal of Molecular Structure, 2023 - Elsevier
Abstract Condensation reaction of 3-formylchromone (1) with 1-ethyl-4-hydroxyquinolin-2
(1H)-one (2) in glacial acetic acid afforded the condensation product 4; in 1: 2 molar ratio …

[HTML][HTML] Larvicidal potential of Cipadessa baccifera leaf extract-synthesized zinc nanoparticles against three major mosquito vectors

G Ramkumar, MS Shivakumar, MA Alshehri… - Green Processing and …, 2022 - degruyter.com
Mosquitoes are important vectors, which transmit many communicable diseases throughout
the world. Synthetic insecticides, such as organophosphate and pyrethroids, are commonly …

Synthesis, crystal structure and antifungal activities of new quinoline derivatives

XP Sun, W Yu, LJ Min, L Han, NB Sun… - Journal of Molecular …, 2023 - Elsevier
A series of new quinoline ester derivatives containing diphenyl ether motif were designed
and synthesized using 4-chlorophenol, 1‑chloro-2-nitrobenzene, as raw materials via four …

Novel 4-aminoquinoline analogs targeting the HIF-1α signaling pathway

YC Wu, MT Lu, PC Chu, CS Chang - Future Medicinal Chemistry, 2023 - Taylor & Francis
Background: The aminoquinoline core exhibits versatile pharmacological properties,
particularly in the area of anticancer activity. This study was designed to investigate the …

Chemistry of Quinolines and their Agrochemical Potential

D Utreja, R Salotra, G Kaur, S Sharma… - Current Organic …, 2022 - ingentaconnect.com
Human population is increasing at an alarming rate which indirectly imposes pressure on
agriculture and food supply. However, crop production is reduced by pathogenic infections …