[HTML][HTML] Recent advances in chemistry and therapeutic potential of functionalized quinoline motifs–a review
OO Ajani, KT Iyaye, OT Ademosun - RSC advances, 2022 - pubs.rsc.org
Quinoline, which consists of benzene fused with N-heterocyclic pyridine, has received
considerable attention as a core template in drug design because of its broad spectrum of …
considerable attention as a core template in drug design because of its broad spectrum of …
Quinoline‐derivatives as privileged scaffolds for medicinal and pharmaceutical chemists: A comprehensive review
The quinoline scaffolds are privileged for their numerous biological activities in the
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …
Deciphering the Mechanism of MRSA Targeting Copper(II) Complexes of NN2 Pincer-Type Ligands
WHO lists AMR as one of the top ten global public health issues. Therefore, constant effort is
needed to develop more efficient antimicrobial drugs. As a result, earth-abundant transition …
needed to develop more efficient antimicrobial drugs. As a result, earth-abundant transition …
Ring opening ring closure reactions with 5, 9-diethyl-7-(chromon-3-yl)-7-hydroquinolino [3′, 4′: 5, 6] pyrano [3, 2-c] quinoline-6, 8 (5H, 9H)-dione with some 1, 2 …
AS Badran, A Ahmed, AI Nabeel, MA Ibrahim - Journal of Molecular …, 2024 - Elsevier
The chemical behaviour of electron deficient substrate 1 was investigated with some 1, 2-bi-
nucleophilic reagents. Reaction of substrate 1 with hydrazine derivatives namely hydrazine …
nucleophilic reagents. Reaction of substrate 1 with hydrazine derivatives namely hydrazine …
Unveiling the crystal structure and quantum properties of 6‑bromo-N-pyridin-4-yl-2-thiophen-2-ylquinoline-4-carboxamide: A promising journey towards predicting its …
TS Shashidhara, CS Navyashree, MK Hema… - Journal of Molecular …, 2023 - Elsevier
The wide range of pharmalogical activity exhibited by quinoline derivatives, due to its fused
benzene ring with pyridine structure, has made them a popular framework for medicinal …
benzene ring with pyridine structure, has made them a popular framework for medicinal …
Nucleophilic reactions with the novel 7-(chromon-3-yl) quinolino [3′, 4′: 5, 6] pyrano [3, 2-c] quinoline: Synthesis, biological and computational studies
A Ahmed, MA Ibrahim, AS Badran - Journal of Molecular Structure, 2023 - Elsevier
Abstract Condensation reaction of 3-formylchromone (1) with 1-ethyl-4-hydroxyquinolin-2
(1H)-one (2) in glacial acetic acid afforded the condensation product 4; in 1: 2 molar ratio …
(1H)-one (2) in glacial acetic acid afforded the condensation product 4; in 1: 2 molar ratio …
[HTML][HTML] Larvicidal potential of Cipadessa baccifera leaf extract-synthesized zinc nanoparticles against three major mosquito vectors
Mosquitoes are important vectors, which transmit many communicable diseases throughout
the world. Synthetic insecticides, such as organophosphate and pyrethroids, are commonly …
the world. Synthetic insecticides, such as organophosphate and pyrethroids, are commonly …
Synthesis, crystal structure and antifungal activities of new quinoline derivatives
XP Sun, W Yu, LJ Min, L Han, NB Sun… - Journal of Molecular …, 2023 - Elsevier
A series of new quinoline ester derivatives containing diphenyl ether motif were designed
and synthesized using 4-chlorophenol, 1‑chloro-2-nitrobenzene, as raw materials via four …
and synthesized using 4-chlorophenol, 1‑chloro-2-nitrobenzene, as raw materials via four …
Novel 4-aminoquinoline analogs targeting the HIF-1α signaling pathway
Background: The aminoquinoline core exhibits versatile pharmacological properties,
particularly in the area of anticancer activity. This study was designed to investigate the …
particularly in the area of anticancer activity. This study was designed to investigate the …
Chemistry of Quinolines and their Agrochemical Potential
Human population is increasing at an alarming rate which indirectly imposes pressure on
agriculture and food supply. However, crop production is reduced by pathogenic infections …
agriculture and food supply. However, crop production is reduced by pathogenic infections …