[HTML][HTML] Meningococcal carriage and disease—population biology and evolution

DA Caugant, MCJ Maiden - Vaccine, 2009 - Elsevier
Meningococcal disease occurs worldwide with incidence rates varying from 1 to 1000 cases
per 100,000. The causative organism, Neisseria meningitidis, is an obligate commensal of …

Atypical, Yet Not Infrequent, Infections with Neisseria Species

MV Humbert, M Christodoulides - Pathogens, 2019 - mdpi.com
Neisseria species are extremely well-adapted to their mammalian hosts and they display
unique phenotypes that account for their ability to thrive within niche-specific conditions. The …

Genome Sequencing Reveals Widespread Virulence Gene Exchange among Human Neisseria Species

PR Marri, M Paniscus, NJ Weyand, MA Rendón… - PloS one, 2010 - journals.plos.org
Commensal bacteria comprise a large part of the microbial world, playing important roles in
human development, health and disease. However, little is known about the genomic …

Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination

S Budroni, E Siena, JCD Hotopp… - Proceedings of the …, 2011 - National Acad Sciences
Molecular data on a limited number of chromosomal loci have shown that the population of
Neisseria meningitidis (Nm), a deadly human pathogen, is structured in distinct lineages …

PAIDB v2. 0: exploration and analysis of pathogenicity and resistance islands

SH Yoon, YK Park, JF Kim - Nucleic acids research, 2015 - academic.oup.com
Pathogenicity is a complex multifactorial process confounded by the concerted activity of
genetic regions associated with virulence and/or resistance determinants. Pathogenicity …

Review and international recommendation of methods for typing Neisseria gonorrhoeae isolates and their implications for improved knowledge of gonococcal …

M Unemo, JAR Dillon - Clinical Microbiology Reviews, 2011 - Am Soc Microbiol
Gonorrhea, which may become untreatable due to multiple resistance to available
antibiotics, remains a public health problem worldwide. Precise methods for typing Neisseria …

The association of virulence factors with genomic islands

SJ Ho Sui, A Fedynak, WWL Hsiao, MGI Langille… - PloS one, 2009 - journals.plos.org
Background It has been noted that many bacterial virulence factor genes are located within
genomic islands (GIs; clusters of genes in a prokaryotic genome of probable horizontal …

Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis

C Schoen, J Blom, H Claus… - Proceedings of the …, 2008 - National Acad Sciences
Neisseria meningitidis is a leading cause of infectious childhood mortality worldwide. Most
research efforts have hitherto focused on disease isolates belonging to only a few …

Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18

SD Bentley, GS Vernikos, LAS Snyder… - PLoS …, 2007 - journals.plos.org
The bacterium Neisseria meningitidis is commonly found harmlessly colonising the mucosal
surfaces of the human nasopharynx. Occasionally strains can invade host tissues causing …

The Genetics of Neisseria Species

E Rotman, HS Seifert - Annual review of genetics, 2014 - annualreviews.org
Neisseria gonorrhoeae and Neisseria meningitidis are closely related organisms that cause
the sexually transmitted infection gonorrhea and serious bacterial meningitis and …