Osteoblasts and adipocytes differentiate from a common pluripotent precursor, the
mesenchymal stem cell (MSC). Studies have identified numerous transcription factors, and …

Presently, there is a high paucity of bone grafts in the United States and worldwide.
Regenerating bone is of prime concern due to the current demand of bone grafts and the …

Human umbilical cord perivascular cells (HUCPVCs) have been shown to have a high
proliferative potential and the capacity to differentiate into an osteogenic phenotype …

Emerging evidence suggests that both human stem cells and mature stromal cells can play
an important role in the development and growth of human malignancies. In contrast to …

Mesenchymal stem cells (MSC) exhibit tropism for sites of tissue damage as well as the
tumor microenvironment. Many of the same inflammatory mediators that are secreted by …

The poor prognosis of patients with aggressive and invasive cancers combined with toxic
effects and short half-life of currently available treatments necessitate development of more …

Mesenchymal stem cells (MSCs) can exhibit a marked tropism towards site of tumors. Many
studies have reported that tumor progression and metastasis increase by MSCs. In contrast …

Fibroblast activation protein (FAP) has emerged as an interesting molecular target used in
the imaging and therapy of various types of cancers. 68Ga-labeled chelator-linked FAP …

Human mesenchymal stem cells (hMSCs) can home to tumor sites and inhibit the growth of
tumor cells. Little is known about the underlying molecular mechanisms that link hMSCs to …

Human umbilical cord (UC) has been a tissue of increasing interest in recent years. Many
groups have shown the stem cell potency of stromal cells isolated from the human UC …