Adult stem cells are promising cellular vehicles for therapy of malignant gliomas as they
have the ability to migrate into these tumors and even track infiltrating tumor cells. However …

Background Previous studies have demonstrated remarkable tropism of mesenchymal stem
cells (MSCs) toward malignant gliomas, making these cells a potential vehicle for delivery of …

In recent years, fibroblast activation protein (FAP) has emerged as an attractive target for the
diagnosis and radiotherapy of cancers using FAP-specific radioligands. Herein, we aimed to …

Irradiation is a standard therapy for gliomas and many other cancers. Tumor necrosis factor-
related apoptosis-inducing ligand (TRAIL) is one of the most promising candidates for …

There is no effective treatment for late stage and metastatic cancers of colorectal, prostate,
pancreatic, breast, glioblastoma and melanoma cancers. Novel treatment modalities are …

Osteoblasts and adipocytes differentiate from a common precursor, the pluripotent
mesenchymal stem cell (MSC) found in bone marrow (BMSC) and adipose tissue (AD …

Fibroblast activation protein (FAP) is overexpressed in cancer-associated fibroblasts in more
than 90% of epithelial tumors. Several radiotracers targeting FAPs have been used in …

Animal and clinical studies have confirmed the therapeutic effect of bone marrow
mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly …

Objective. To evaluate the feasibility of visualizing bone marrow-derived human
mesenchymal stem cells (MSCs) labeled with a gold-coated magnetic resonance (MR) …

Research has provided evidence that tumor growth depends on the interaction of tumor cells
with stromal cells, as already suggested in 1889 by Paget. Experimental and clinical studies …