The foundation for the anatomical and functional complexity of the vertebrate central
nervous system is laid during embryogenesis. After Spemann's organizer and its derivatives …

Mounting evidence indicates that Wnt signaling is relevant to pathophysiology of diverse
mental illnesses including schizophrenia, bipolar disorder, and autism spectrum disorder. In …

The thalamus plays a central coordinating role in the brain. Thalamic neurons are organized
into spatially distinct nuclei, but the molecular architecture of thalamic development is poorly …

The origin of the pentaradial body plan of echinoderms from a bilateral ancestor is one of the
most enduring zoological puzzles,. Because echinoderms are defined by morphological …

Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a
diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells …

Wnt-ligands are among key morphogens that mediate patterning of the anterior territories of
the developing brain in mammals. We qualified the role of Wnt-signals in regional …

Initial axial patterning of the neural tube into forebrain, midbrain, and hindbrain primordia
occurs during gastrulation. After this patterning phase, further diversification within the brain …

Thalamocortical axons must cross a complex cellular terrain through the developing
forebrain, and this terrain has to be understood for us to learn how thalamocortical axons …

In this review we discuss recent advances in the understanding of the development of
forebrain projections attending to their origin, fate determination, and axon guidance. Major …

The capacity for regeneration is broad in the animal kingdom. Planarians are flatworms that
can regenerate any missing body part and their regenerative powers have combined with …