Gynecologic cancers and non-coding RNAs: epigenetic regulators with emerging roles

ZS Razavi, V Tajiknia, S Majidi, M Ghandali… - Critical reviews in …, 2021 - Elsevier
Gynecologic cancers involve the female genital organs, such as the vulva, vagina, cervix,
endometrium, ovaries, and fallopian tubes. The occurrence and frequency of gynecologic …

Epithelioid and spindle cell rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusion: report of two cases

JSA Chrisinger, B Wehrli, BC Dickson, S Fasih… - Virchows Archiv, 2020 - Springer
Abstract The WHO Classification of Tumors of Soft Tissue and Bone divides
rhabdomyosarcoma (RMS) into alveolar, embryonal, pleomorphic, and spindle …

Circular RNA hsa_circ_0023404 exerts an oncogenic role in cervical cancer through regulating miR-136/TFCP2/YAP pathway

J Zhang, X Zhao, J Zhang, X Zheng, F Li - Biochemical and biophysical …, 2018 - Elsevier
Cervical cancer (CC) is one of the most prevalent malignances among women. However,
the mechanism underlying CC development remains elusive. Recently, circular RNAs …

TFCP2/TFCP2L1/UBP1 transcription factors in cancer

G Kotarba, E Krzywinska, AI Grabowska, A Taracha… - Cancer letters, 2018 - Elsevier
The TFCP2/Grainyhead family of transcription factors is divided into two distinct subfamilies,
one of which includes the Grainyhead-like 1-3 (GRHL1-3) proteins and the other consists of …

FET(EWSR1)-TFCP2 Rhabdomyosarcoma: An Additional Example of this Aggressive Variant with Predilection for the Gnathic Bones

IG Koutlas, DR Olson, J Rawwas - Head and neck pathology, 2021 - Springer
An example of a mandibular rhabdomyosarcoma in a 15-year-old male is described
featuring EWSR1-TFCP2 fusion with homolateral lymph node metastasis and apparent …

A feedback loop comprising EGF/TGFα sustains TFCP2-mediated breast cancer progression

Y Zhao, N Kaushik, JH Kang, NK Kaushik, SH Son… - Cancer research, 2020 - AACR
Stemness and epithelial–mesenchymal transition (EMT) are two fundamental characteristics
of metastasis that are controlled by diverse regulatory factors, including transcription factors …

Novel EWSR1::UBP1 fusion expands the spectrum of spindle cell rhabdomyosarcomas

S El Zein, L Djeroudi, S Reynaud… - Genes …, 2022 - Wiley Online Library
Over the last decade, the development of next‐generation sequencing techniques has led to
the molecular dismantlement of adult and pediatric sarcoma, with the identification of …

Human umbilical cord mesenchymal stem cell-derived extracellular vesicles loaded with TFCP2 activate Wnt/β-catenin signaling to alleviate preeclampsia

Z Yang, X Jia, Q Deng, M Luo, Y Hou, J Yue… - International …, 2023 - Elsevier
Background Failures in invasive extravillous trophoblasts (EVTs) migration into the maternal
uterus have been noticed in preeclampsia (PE). Human umbilical cord mesenchymal stem …

[HTML][HTML] Pharmacologic manipulation of late SV40 factor suppresses Wnt Signaling and inhibits growth of allogeneic and syngeneic colon cancer xenografts

S Lotfollahzadeh, D Lo, EA York, MA Napoleon… - The American Journal of …, 2022 - Elsevier
Aberrant hyperactivation of Wnt signaling, driven by nuclear β-catenin in the colonic
epithelium, represents the seminal event in the initiation and progression of colorectal …

TFCP2 as a therapeutic nexus: unveiling molecular signatures in cancer

N Kaushik, A Jaiswal, P Bhartiya, EH Choi… - Cancer and Metastasis …, 2024 - Springer
Tumor suppressor genes and proto-oncogenes comprise most of the complex genomic
landscape associated with cancer, with a minimal number of genes exhibiting dual-context …