Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

Innate and adaptive immune cells patrol and survey throughout the human body and
sometimes reside in the tumor microenvironment (TME) with a variety of cell types and …

The Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathway is
involved in many immunological processes, including cell growth, proliferation …

Breast cancer is a severe problem worldwide due to an increase in mortality and prevalence
among women. Despite early diagnostic procedures as well as advanced therapies, more …

The tumor microenvironment is overwhelmingly dictated by macrophages, intimately
affiliated with tumors, exercising pivotal roles in multiple processes, including angiogenesis …

The permeability of glioblastoma, as well as its escaping the immune system, makes them
one of the most deadly human malignancies. By avoiding programmed cell death …

Gene therapy can be used as a cancer therapy by affecting signaling networks participating
in the aggressive behavior of tumors. Small interfering RNA (siRNA) is a genetic tool …

Anti-neoplastic agents for cancer treatment utilize many different mechanisms of action and,
when combined, can result in potent inhibition of cancer growth. Combination therapies can …

Nanomedicine has emerged as a promising platform for disease treatment and much
progress has been achieved in the clinical translation for cancer treatment. Several types of …

Despite community vaccination against coronavirus disease 2019 (COVID-19) and reduced
mortality, there are still challenges in treatment options for the disease. Due to the …