Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response

DW Hawman, KA Stoermer, SA Montgomery… - Journal of …, 2013 - Am Soc Microbiol
Chikungunya virus (CHIKV) is a reemerging mosquito-borne pathogen that causes
incapacitating disease in humans characterized by intense joint pain that can persist for …

[HTML][HTML] Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays

L Pohjala, A Utt, M Varjak, A Lulla, A Merits, T Ahola… - PloS one, 2011 - journals.plos.org
Chikungunya virus (CHIKV), an alphavirus, has recently caused epidemic outbreaks and is
therefore considered a re-emerging pathogen for which no effective treatment is available. In …

[HTML][HTML] A mouse model of chikungunya virus–induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence

TE Morrison, L Oko, SA Montgomery… - The American journal of …, 2011 - Elsevier
Chikungunya virus (CHIKV), an emerging mosquito-borne Alphavirus, causes debilitating
rheumatic disease in humans that can last for weeks to months. Starting in 2004, a CHIKV …

Chikungunya chronic disease: a systematic review and meta-analysis

ES Paixão, LC Rodrigues, MCN Costa… - Transactions of The …, 2018 - academic.oup.com
Background Chikungunya is a mosquito-borne disease caused by an arthritogenic
alphavirus, with four genotypes: East Central South African (ECSA), West African, ECSA …

[HTML][HTML] Chikungunya: epidemiology

LR Petersen, AM Powers - F1000Research, 2016 - ncbi.nlm.nih.gov
Chikungunya virus is a mosquito-borne alphavirus that causes fever and debilitating joint
pains in humans. Joint pains may last months or years. It is vectored primarily by the tropical …

[HTML][HTML] Chikungunya virus infection

F Simon, E Javelle, M Oliver, I Leparc-Goffart… - Current infectious …, 2011 - Springer
Chikungunya virus (CHIKV) is an alphavirus transmitted by mosquitoes, mostly Aedes
aegypti and Aedes albopictus. After half a century of focal outbreaks of acute febrile …

Sindbis virus as a human pathogen—epidemiology, clinical picture and pathogenesis

S Adouchief, T Smura, J Sane… - Reviews in medical …, 2016 - Wiley Online Library
Sindbis virus (SINV; family Togaviridae, genus Alphavirus) is an enveloped RNA virus
widely distributed in Eurasia, Africa, Oceania and Australia. SINV is transmitted among its …

[HTML][HTML] Chikungunya fever: a clinical and virological investigation of outpatients on Reunion Island, South-West Indian Ocean

SD Thiberville, V Boisson, J Gaudart… - PLoS neglected …, 2013 - journals.plos.org
Background Chikungunya virus (CHIKV) is responsible for acute febrile polyarthralgia and,
in a proportion of cases, severe complications including chronic arthritis. CHIKV has spread …

[HTML][HTML] A review of chikungunya virus-induced arthralgia: clinical manifestations, therapeutics, and pathogenesis

BA Goupil, CN Mores - The open rheumatology journal, 2016 - ncbi.nlm.nih.gov
Background: Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that circulates
predominantly in tropical and subtropical regions, potentially affecting over 1 billion people …

Fatal outcome of chikungunya virus infection in Brazil

STS de Lima, WM de Souza… - Clinical Infectious …, 2021 - academic.oup.com
Background Chikungunya virus (CHIKV) emerged in the Americas in 2013 and has caused
approximately 2.1 million cases and> 600 deaths. A retrospective investigation was …