Interactions between blood platelets and polymorphonuclear leukocytes (PMN) influence
cell reactivity. We have examined the effects of inhibiting platelet and PMN cyclooxygenase …

Studies from our laboratory have demonstrated that epinephrine via alpha2-adrenoreceptor
modulation can restore the sensitivity of aspirin-treated platelets to the action of agonists …

Exposure of platelets to phospholipase A 2 selectively obliterates the aggregation response
of human platelets to the action of epinephrine. This treatment does not impair the affinity of …

Studies in animal models are useful to understand the basic mechanisms involved in
hemostasis and the functional differences among species. Ultrastructural observations led …

BACKGROUND AND OBJECTIVE: The role of glycoprotein Ib (GPIb) in platelet adhesion to
subendothelium is well established in human species. However, the interaction of GPIb and …

abstract Study objective–This study was performed to see whether ethanol could potentiate
the inhibitory effect of aspirin on recurrent platelet thrombus formation and subsequent …

Background Pharmacological inhibition of arachidonic acid metabolism has proven
therapeutically useful in the prevention of cardiovascular events. Methods We have …

Salient Features: This is the best one among all monographs on Platelets, put together by
Professor Gundu HR Rao. There is the description of the roles of the cells in hemostasis and …

BACKGROUND AND OBJECTIVE: There is evidence suggesting that von Willebrand factor
(VWF) from high purity factor VIII concentrates could be of clinical use in the management of …

Introduction 3. Platelet Physiology 4. Arachidonic Acid Metabolism 5. Platelet Hyperfunction
6. Vascular Dysfunction 7. Clinical Use of Aspirin 8. Aspirin Resistance 9. Prevalence of …