Proaggregatory effect of epinephrine on rabbit platelets inhibited by ticlopidine

CK Derian, RJ Gould, PA Friedman - Thrombosis research, 1990 - Elsevier
Ticlopidine is a potent inhibitor of ADP-induced aggregation of rabbit platelets ex vivo. In
vivo, however, multiple agonists play a role in platelet activation. In this study, we examined …

Epinephrine-induced reversal of aspirin effects on platelet deformability

CM Smith II, SM Burris, GHR Rao, JG White - Thrombosis research, 1988 - Elsevier
The present study has evaluated the influence of epinephrine on the resistance of platelets
to aspiration into micropipettes, and the effect of epinephrine on the altered deformability of …

A deleterious effect of aspirin on the antithrombotic properties of endothelial cells is not observed with platelets previously exposed to aspirin: studies in a flow system

M Alemany, MR Hernandez, J Bozzo, A Bono… - Platelets, 1996 - Taylor & Francis
We have explored both the independent and combined effects of aspirin on cultured
endothelial cells and platelets, and its influence on platelet deposition onto an extracellular …

Antiplatelet therapy in coronary disease: what agent to use, when, and how?

P Theroux - Journal of Thrombosis and Thrombolysis, 1998 - Springer
The striking efficacy of aspirin in preventing the thrombotic complications associated with
cardiovascular diseases has stimulated the development and clinical evaluation of a new …

Potentiation of the Antiplatelet Effect of Aspirin by the Calcium Channel Antagonist Amlodipine

JD Folts, JW Hamilton, CK Stone - Calcium Antagonists: Pharmacology …, 1993 - Springer
The primary role of platelets in the precipitation of unstable angina, myocardial infarction,
and sudden death is generally accepted (1). Platelet thrombi are also thought to be …

[PDF][PDF] Aspirin: expectations and limitations

GHR Rao - JAPI, 2008 - researchgate.net
Gundu HR Rao* can be recommended. According to some physicians, non-compliance
seems to be a significant mediator of poor out come. Platelets exposed to aspirin may exhibit …

[DOC][DOC] Aspirin Therapy: expectations and limitations

GHR Rao - researchgate.net
South Asians (Indians, Pakistanis, Bangladeshis and Sri Lankans) have the highest
incidence of Coronary Artery Disease (CAD) compared to any other ethnic group in the …

Platelet Dysfunction in Type-2 Diabetes Mellitus

GHR Rao - Mechanisms of Vascular Defects in Diabetes Mellitus, 2017 - Springer
Abstract According to the Diabetes Atlas of the World, published by the International
Diabetes Federation (IDF Diabetes Atlas, 7th edn, 2015), India has currently, over 70 million …

[DOC][DOC] Development of a Lab-on-a-Chip Assay for Monitoring Platelet and Vessel Wall Production of Prostanoids.

GHR Rao, S Vashist - researchgate.net
Platelets play a very important role in the pathogenesis of acute vascular events leading to
thrombosis of the coronary and cerebral arteries. Blockage of these arteries leading to …

[DOC][DOC] Development of Point-of-Care Device for Cardiovascular Applications

GHR Rao - researchgate.net
Blood platelets play a very important role in the pathogenesis of heart attacks and stroke (1-
4). Therefore, several million individuals all over the world take aspirin, an irreversible …