Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons
The main breakthrough in tumor immunotherapy was the discovery of immune checkpoint
(IC) proteins, which act as a potent suppressor of the immune system by a myriad of …
(IC) proteins, which act as a potent suppressor of the immune system by a myriad of …
Radiotherapy and immunology
The majority of cancer patients receive radiotherapy during the course of treatment,
delivered with curative intent for local tumor control or as part of a multimodality regimen …
delivered with curative intent for local tumor control or as part of a multimodality regimen …
Radiation therapy for extensive-stage small-cell lung cancer in the era of immunotherapy
Y Tian, J Ma, X Jing, X Zhai, Y Li, Z Guo, J Yu, H Zhu - Cancer Letters, 2022 - Elsevier
Unlike non-small-cell lung cancer (NSCLC), the progression of small-cell lung cancer
(SCLC) is slow. Extensive-stage SCLC (ES-SCLC) is a serious threat to human health, with …
(SCLC) is slow. Extensive-stage SCLC (ES-SCLC) is a serious threat to human health, with …
[HTML][HTML] Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in locally advanced head …
M Hecht, M Eckstein, S Rutzner… - … for ImmunoTherapy of …, 2022 - ncbi.nlm.nih.gov
Purpose The first aim of the trial is to study feasibility of combined programmed death protein
ligand 1/cytotoxic T-lymphocyte-associated protein 4 inhibition concomitant to radiotherapy …
ligand 1/cytotoxic T-lymphocyte-associated protein 4 inhibition concomitant to radiotherapy …
[HTML][HTML] Tackling the current dilemma of immunotherapy in extensive-stage small cell lung cancer: A promising strategy of combining with radiotherapy
K Kang, Y Wu, Z Yao, Y Lu - Cancer Letters, 2023 - Elsevier
Progress in the treatment of small cell lung cancer (SCLC) has been modest over the past
decades until the advent of immune checkpoint inhibitors, which have redefined the …
decades until the advent of immune checkpoint inhibitors, which have redefined the …
[HTML][HTML] A real-world evaluation of atezolizumab plus platinum-etoposide chemotherapy in patients with extensive-stage SCLC in Canada
AA Elegbede, AJ Gibson, AS Fung, WY Cheung… - JTO clinical and …, 2021 - Elsevier
Introduction The real-world data evaluating treatment outcomes of atezolizumab plus
carboplatin-etoposide chemotherapy (atezolizumab) for extensive-stage SCLC (ESCLC) are …
carboplatin-etoposide chemotherapy (atezolizumab) for extensive-stage SCLC (ESCLC) are …
Global research landscape and trends of lung cancer immunotherapy: a bibliometric analysis
Y Liu, X Cheng, X Han, X Cheng, S Jiang… - Frontiers in …, 2022 - frontiersin.org
Background Immunotherapy for lung cancer has been a hot research area for years. This
bibliometric analysis aims to present the research trends on lung cancer immunotherapy …
bibliometric analysis aims to present the research trends on lung cancer immunotherapy …
Clinical predictors of survival in patients with relapsed/refractory small-cell lung cancer treated with checkpoint inhibitors: a German multicentric real-world analysis
JA Stratmann, R Timalsina, A Atmaca… - Therapeutic …, 2022 - journals.sagepub.com
Objectives: Small-cell lung cancer (SCLC) is a lung malignancy with high relapse rates and
poor survival outcomes. Treatment-resistant disease relapse occurs frequently and effective …
poor survival outcomes. Treatment-resistant disease relapse occurs frequently and effective …
Progress in the clinical application of immune checkpoint inhibitors in small cell lung cancer
J He, Q Hu - Frontiers in Immunology, 2023 - frontiersin.org
Small cell lung cancer (SCLC) is a refractory cancer with poor prognosis due to its
aggressive malignancy and high rates of metastasis, recurrence and drug resistance. These …
aggressive malignancy and high rates of metastasis, recurrence and drug resistance. These …
Immune checkpoint inhibitors and chemoradiation for limited-stage small cell lung cancer
B Schlick, MD Shields, JA Marin-Acevedo… - … Treatment Options in …, 2022 - Springer
Opinion statement Limited-stage small cell lung cancer (LS-SCLC) is a potentially curable
disease. However, most patients develop disease relapse shortly after definitive treatment …
disease. However, most patients develop disease relapse shortly after definitive treatment …