A new spectral shift-based method to characterize molecular interactions
A Langer, A Lüdecke, T Bartoschik… - ASSAY and Drug …, 2022 - liebertpub.com
There are many fluorescence-based applications that can be used to characterize molecular
interactions. However, available methods often depend on site-specific labeling techniques …
interactions. However, available methods often depend on site-specific labeling techniques …
Cytosine-5 methylation-directed construction of a Au nanoparticle-based nanosensor for simultaneous detection of multiple DNA methyltransferases at the single …
DNA methylation at cytosine/guanine dinucleotide islands (CpGIs) is the most prominent
epigenetic modification in prokaryotic and eukaryotic genomes. DNA methyltransferases …
epigenetic modification in prokaryotic and eukaryotic genomes. DNA methyltransferases …
Enzyme-free and isothermal discrimination of microRNA point mutations using a DNA split proximity circuit with turn-on fluorescence readout
MicroRNAs (miRNAs) hold immense potential as disease biomarkers, yet their short lengths
and high sequence homology pose unique challenges in detection. Conventional methods …
and high sequence homology pose unique challenges in detection. Conventional methods …
Handhold-mediated strand displacement: a nucleic acid based mechanism for generating far-from-equilibrium assemblies through templated reactions
The use of templates is a well-established method for the production of sequence-controlled
assemblies, particularly long polymers. Templating is canonically envisioned as akin to a …
assemblies, particularly long polymers. Templating is canonically envisioned as akin to a …
Choice of fluorophore affects dynamic DNA nanostructures
The ability to dynamically remodel DNA origami structures or functional nanodevices is
highly desired in the field of DNA nanotechnology. Concomitantly, the use of fluorophores to …
highly desired in the field of DNA nanotechnology. Concomitantly, the use of fluorophores to …
Displacement and dissociation of oligonucleotides during DNA hairpin closure under strain
The hybridization kinetic of an oligonucleotide to its template is a fundamental step in many
biological processes such as replication arrest, CRISPR recognition, DNA sequencing, DNA …
biological processes such as replication arrest, CRISPR recognition, DNA sequencing, DNA …
An atomistic view on carbocyanine photophysics in the realm of RNA
FD Steffen, RKO Sigel, R Börner - Physical Chemistry Chemical …, 2016 - pubs.rsc.org
Carbocyanine dyes have a long-standing tradition in fluorescence imaging and
spectroscopy, due to their photostability and large spectral separation between individual …
spectroscopy, due to their photostability and large spectral separation between individual …
DNA hybridisation kinetics using single-molecule fluorescence imaging
R Andrews - Essays in Biochemistry, 2021 - portlandpress.com
Deoxyribonucleic acid (DNA) hybridisation plays a key role in many biological processes
and nucleic acid biotechnologies, yet surprisingly there are many aspects about the process …
and nucleic acid biotechnologies, yet surprisingly there are many aspects about the process …
Разнообразие праймеров для ПЦР и принципы их подбора
РР Гарафутдинов, АХ Баймиев, ГВ Малеев… - Биомика, 2019 - elibrary.ru
Праймеры являются очень важным компонентом ПЦР, поскольку специфичность
амплификации зависит в первую очередь от них. Хотя на эффективность ПЦР влияет …
амплификации зависит в первую очередь от них. Хотя на эффективность ПЦР влияет …
Trimethine cyanine dyes as NA-sensitive probes for visualization of cell compartments in fluorescence microscopy
We propose symmetrical cationic trimethine cyanine dyes with β-substituents in the
polymethine chain based on modified benzothiazole and benzoxazole heterocycles as …
polymethine chain based on modified benzothiazole and benzoxazole heterocycles as …