Resume The efficiency of Polymerase Chain Reaction (PCR) depends on multiple factors.
The primers are very important components of PCR which determine the specificity of …

Methods for the quantification of antisense oligonucleotides (AONs) provide insightful
information on biodistribution and intracellular trafficking. However, the established methods …

Single-molecule imaging of fluorescently labeled biomolecules is a powerful technique for
measuring association interactions; however, care must be taken to ensure that the …

Fluorescence-free micro-manipulation of nucleic acids (NA) allows the functional
characterization of DNA/RNA processing proteins, without the interference of labels, but …

Oligonucleotide aptamers can be converted into structure-switching biosensors by
incorporating a short, typically labeled oligonucleotide that is complementary to the analyte …

The sensitivity of FRET-based sensing is usually limited by the spectral overlaps of the FRET
donor and acceptor, which generate a poor signal-to-noise ratio. To overcome this limitation …

Characterization of DNA at solid/liquid interfaces remains a challenge because most surface-
sensitive techniques are unable to provide quantitative insight into the base content, length …

We study phase behaviour of lipid-bilayer vesicles functionalised by ligand–receptor
complexes made of synthetic DNA by introducing a modelling framework and a dedicated …

Controllable strong interactions between a nanocavity and a single emitter is important to
manipulating optical emission in a nanophotonic system but challenging to achieve. Herein …

After Ctr1-mediated cell uptake, copper (Cu) is transported by the cytoplasmic Cu chaperone
Atox1 to P1B type ATPases ATP7A and ATP7B in the Golgi network, for incorporation into …