Best practice for improved accuracy: A critical reassessment of van't Hoff analysis of melt curves

JM Majikes, M Zwolak, JA Liddle - Biophysical Journal, 2022 - cell.com
Biomolecular thermodynamics, particularly for DNA, are frequently determined via van't Hoff
analysis of optically measured melt curves. Accurate and precise values of thermodynamic …

[PDF][PDF] and the Zincke Reaction

M Wong - sussex.figshare.com
Mechanochemistry is scientific discipline that has been identified and developed in the last
150 years. It has its roots in mechanical activation which is concerned with structural …

Impacts of fluorescent base analogue substitution on the folding of a riboswitch

JE Hoeher, MA Veirs, JR Widom - bioRxiv, 2021 - biorxiv.org
Riboswitches are gene-regulating mRNA segments most commonly found in bacteria. A
riboswitch contains an aptamer domain that binds to a ligand, causing a conformational …

Unique solvatochromism of cyanine/saponite hybrid systems

A Czímerová, S Sas, A Čeklovský - Applied Clay Science, 2017 - Elsevier
The present study is primarily focused on the investigation of spectral properties of cationic
cyanine dye (1, 1′-diethyl-4, 4′-carbocyanine iodide, denoted as “NK5”) adsorbed into the …

[PDF][PDF] Studying the Structural Dynamics and Aptamer-Ligand Interactions in the Cocaine-Binding Aptamer through Fluorescence Spectroscopy

AA Shoara - 2022 - yorkspace.library.yorku.ca
Since its first report in 1990, aptamers have been utilized in biosensor modeling
technologies. One of the most important advantages of using aptamers is the structural …

Выявление антимикробной активности у потенциальных каучуконосов флоры Южного Урала

БР Кулуев, ГР Ахметова, КЮ Швец, АА Мулдашев… - Биомика, 2019 - elibrary.ru
Значительную актуальность представляет возможность получения натурального
каучука из растительного материала, выращенного на территории стран с умеренным …

Desenvolvimento de uma representação mesoscópica para marcadores fluorescentes em DNA e predição de intensidade de fluorescência

PM de Moura - 2020 - repositorio.ufmg.br
Marcadores fluorescentes atadosa moléculas de DNA sao muito usados nas áreas de
biomedicina e biotecnologia, por exemplo, e podem ser estudados aplicando-se modelos …

Measurement of Kinetics of Hammerhead Ribozyme Cleavage Reactions Using Toehold Mediated Strand Displacement

JB Kapadia, N Kharma, AN Davis, N Kamel, J Perreault - bioRxiv, 2020 - biorxiv.org
This paper presents a probe comprising a fluorophore and a quencher, enabling
measurement of hammerhead ribozyme cleavage reactions, without labeled RNA …

Advancements in Non-Enzymatic Nucleic Acid Diagnostics for Point-of-Care Testing Using Enantiomeric Left-Handed DNA

Z Zimmers - 2021 - ir.vanderbilt.edu
Nucleic acids have emerged as leading biomarkers for diagnostic technologies, as they
allow for extremely specific discrimination of targets via base-pair binding. Overcoming the …

[PDF][PDF] Polyheterocyclic compound in the synthesis and spectral studies of some novel methine cyanine dyes

HA Shindy, AK Khalafallah, MM Goma… - Revue Roumaine de …, 2016 - revroum.lew.ro
Cyanine dyes1-14 are interesting class of organic heterocyclic dyes which have a wide
spectrum of uses and applications in several fields of science and technology. These …