Stem cell therapy for spinal cord injury

L Huang, C Fu, F Xiong, C He, Q Wei - Cell transplantation, 2021 - journals.sagepub.com
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues,
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …

[HTML][HTML] Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury

H Suzuki, Y Imajo, M Funaba, H Ikeda… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

Cell therapies for spinal cord injury: a review of the clinical trials and cell-type therapeutic potential

BF Ribeiro, BC da Cruz, BM de Sousa, PD Correia… - Brain, 2023 - academic.oup.com
Spinal cord injury (SCI) is an as yet untreatable neuropathology that causes severe
dysfunction and disability. Cell-based therapies hold neuroregenerative and neuroprotective …

[HTML][HTML] A swift expanding trend of extracellular vesicles in spinal cord injury research: a bibliometric analysis

F Zhiguo, W Ji, C Shenyuan, Z Guoyou, K Chen… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) in the field of spinal cord injury (SCI) have garnered significant
attention for their potential applications in diagnosis and therapy. However, no bibliometric …

[HTML][HTML] Advanced approaches to regenerate spinal cord injury: the development of cell and tissue engineering therapy and combinational treatments

J Saremi, N Mahmoodi, M Rasouli, FE Ranjbar… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …

How can clinical safety and efficacy concerns in stem cell therapy for spinal cord injury be overcome?

N Hejrati, R Wong, M Khazaei… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Spinal cord injury (SCI) can lead to severe neurological dysfunction. Despite
scientific and medical advances, clinically effective regenerative therapies including stem …

[HTML][HTML] Mesenchymal stem cell therapy in traumatic spinal cord injury: a systematic review

R Montoto-Meijide, R Meijide-Faílde… - International Journal of …, 2023 - mdpi.com
Recovery from a traumatic spinal cord injury (TSCI) is challenging due to the limited
regenerative capacity of the central nervous system to restore cells, myelin, and neural …

[HTML][HTML] Engineered extracellular vesicles derived from primary M2 macrophages with anti-inflammatory and neuroprotective properties for the treatment of spinal cord …

C Zhang, D Li, H Hu, Z Wang, J An, Z Gao… - Journal of …, 2021 - Springer
Background Uncontrollable inflammation and nerve cell apoptosis are the most destructive
pathological response after spinal cord injury (SCI). So, inflammation suppression combined …

Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances

SM Hosseini, B Borys, S Karimi-Abdolrezaee - Brain, 2024 - academic.oup.com
Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

[Retracted] Recent Advances in Cell and Functional Biomaterial Treatment for Spinal Cord Injury

T Liu, W Zhu, X Zhang, C He, X Liu… - BioMed Research …, 2022 - Wiley Online Library
Spinal cord injury (SCI) is a devastating central nervous system disease caused by
accidental events, resulting in loss of sensory and motor function. Considering the multiple …