The worldwide pandemic caused by the novel acute respiratory syndrome coronavirus 2 has
resulted in a new and lethal disease termed coronavirus disease-2019 (COVID-19) …

Mexico has been positioned as the country with the highest mortality attributed to myocardial
infarction among the members of the Organization for Economic Cooperation and …

ContextThe optimal pharmacological strategy for bridging the delay between admission and
performance of percutaneous coronary intervention (PCI) in patients with acute myocardial …

Given the overall superiority of primary PCI over hospitaladministered fibrinolysis, 2 the
former has emerged as the treatment of choice when the facilities and a high-volume …

Aims Pharmaco-invasive percutaneous coronary intervention (PI-PCI) is recommended for
patients with ST-elevation myocardial infarction (STEMI) who are unable to undergo timely …

The restoration of epicardial and myocardial flow remains the primary goal of reperfusion
therapy in patients with ST-segment elevation myocardial infarction, but the optimal method …

Reteplase (Retavase®) is a plasminogen activator, mimicking endogenous tissue
plasminogen activator (t-PA), a serine protease, converting plasminogen to plasmin and …

artery hypothesis. 16 GUSTO-I also indicated that the more potent rt-PA induced a 0.2%
absolute excess of intracranial hemorrhage (0.7% versus 0.5%). In aggregate, when …

In this issue of the European Heart Journal, De Luca et al., demonstrate that among 1072
patients with ST-segment elevation myocardial infarction (STEMI) treated by primary …

To determine whether tenecteplase (TNK-t-PA), a bioengineered variant of tissue-type
plasminogen activator (t-PA) designed to accelerate thrombolysis, exhibits favorable …