Enzyme promiscuity: mechanism and applications

K Hult, P Berglund - Trends in biotechnology, 2007 - cell.com
Introductory courses in biochemistry teach that enzymes are specific for their substrates and
the reactions they catalyze. Enzymes diverging from this statement are sometimes called …

C− C bond-forming lyases in organic synthesis

M Brovetto, D Gamenara, P Saenz Mendez… - Chemical …, 2011 - ACS Publications
Lyases are enzymes that catalyze the bond construction and breaking by means other than
hydrolysis or redox reactions. Such enzymes are particular in the sense that they only …

Biocatalytic promiscuity: the first lipase-catalysed asymmetric aldol reaction

C Li, XW Feng, N Wang, YJ Zhou, XQ Yu - Green Chemistry, 2008 - pubs.rsc.org
Biocatalytic promiscuity: the first lipase -catalysed asymmetric aldol reaction - Green Chemistry
(RSC Publishing) DOI:10.1039/B803406K Royal Society of Chemistry View PDF VersionPrevious …

Lipase-catalysed direct Mannich reaction in water: utilization of biocatalytic promiscuity for C–C bond formation in a “one-pot” synthesis

K Li, T He, C Li, XW Feng, N Wang, XQ Yu - Green Chemistry, 2009 - pubs.rsc.org
Lipase-catalysed direct Mannich reaction in water : utilization of biocatalytic promiscuity for
C–C bond formation in a “one-pot” synthesis - Green Chemistry (RSC Publishing) DOI:10.1039/B817524A …

Biocatalytic promiscuity

MS Humble, P Berglund - European Journal of Organic …, 2011 - Wiley Online Library
Enzymes are attractive catalysts because of their promiscuity and their ability to perform
highly regio‐, chemo‐and stereoselective transformations. Enzyme promiscuity allows …

Hydroxynitrile lyase‐catalyzed enzymatic nitroaldol (Henry) reaction

M Gruber‐Khadjawi, T Purkarthofer… - Advanced Synthesis …, 2007 - Wiley Online Library
The hydroxynitrile lyase from Hevea brasiliensis not only catalyzes–according to the natural
activity of this enzyme–the formation and cleavage of cyanohydrins but also the reaction of …

Lipase-catalysed decarboxylative aldol reaction and decarboxylative Knoevenagel reaction

XW Feng, C Li, N Wang, K Li, WW Zhang, Z Wang… - Green …, 2009 - pubs.rsc.org
Lipase-catalysed decarboxylative aldol reaction and decarboxylative Knoevenagel reaction -
Green Chemistry (RSC Publishing) DOI:10.1039/B914653A Royal Society of Chemistry View …

Utilization of biocatalytic promiscuity for direct Mannich reaction

T He, K Li, MY Wu, XW Feng, N Wang, HY Wang… - Journal of molecular …, 2010 - Elsevier
A lipase-catalyzed direct Mannich reaction of arylamines with aromatic aldehydes and
ketones including cyclohexanone, butanone and 1-hydroxy-2-propanone was developed …

Enzyme-catalyzed Henry (nitroaldol) reaction

RC Tang, Z Guan, YH He, W Zhu - Journal of Molecular Catalysis B …, 2010 - Elsevier
Enzyme-catalyzed Henry (nitroaldol) reaction - ScienceDirect Skip to main contentSkip to
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Biocatalytic domino reaction: synthesis of 2 H-1-benzopyran-2-one derivatives using alkaline protease from Bacillus licheniformis

CH Wang, Z Guan, YH He - Green chemistry, 2011 - pubs.rsc.org
A novel BLAP (alkaline protease from Bacillus licheniformis) catalyzed synthesis of 2H-1-
benzopyran-2-one derivatives was achieved by domino Knoevenagel/intramolecular …