The tolerogenic function of regulatory T cells in pregnancy and cancer
N Jørgensen, G Persson, TVF Hviid - Frontiers in immunology, 2019 - frontiersin.org
Regulatory T cells, a subpopulation of suppressive T cells, are potent mediators of self-
tolerance and essential for the suppression of triggered immune responses. The immune …
tolerance and essential for the suppression of triggered immune responses. The immune …
Mechanisms of human FoxP3+ Treg cell development and function in health and disease
M Attias, T Al-Aubodah… - Clinical & experimental …, 2019 - academic.oup.com
Regulatory T (Treg) cells represent an essential component of peripheral tolerance. Given
their potently immunosuppressive functions that is orchestrated by the lineage-defining …
their potently immunosuppressive functions that is orchestrated by the lineage-defining …
Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells
NAJ Dawson, I Rosado-Sánchez… - Science Translational …, 2020 - science.org
Antigen-specific regulatory T cells (Tregs) engineered with chimeric antigen receptors
(CARs) are a potent immunosuppressive cellular therapy in multiple disease models and …
(CARs) are a potent immunosuppressive cellular therapy in multiple disease models and …
[HTML][HTML] Chimeric antigen receptor costimulation domains modulate human regulatory T cell function
Tregs are key modulators of inflammation and are important for the maintenance of
peripheral tolerance. Adoptive immunotherapy with polyclonal Tregs holds promise in organ …
peripheral tolerance. Adoptive immunotherapy with polyclonal Tregs holds promise in organ …
Regulatory T lymphocytes in periodontitis: a translational view
Periodontitis is a chronic immuno‐inflammatory disease in which the disruption of the
balance between host and microbiota interactions is key to the onset and progression of the …
balance between host and microbiota interactions is key to the onset and progression of the …
CAR Treg: A new approach in the treatment of autoimmune diseases
SA Beheshti, K Shamsasenjan, M Ahmadi… - International …, 2022 - Elsevier
Regulatory T cells (Tregs) have the role of regulating self-tolerance, and suppressing
immune responses. Defects in Treg function and number can lead to in loss of tolerance or …
immune responses. Defects in Treg function and number can lead to in loss of tolerance or …
Ex Vivo Expanded Human Non-Cytotoxic CD8+CD45RClow/− Tregs Efficiently Delay Skin Graft Rejection and GVHD in Humanized Mice
S Bézie, D Meistermann, L Boucault, S Kilens… - Frontiers in …, 2018 - frontiersin.org
Both CD4+ and CD8+ Tregs play a critical role in the control of immune responses and
immune tolerance; however, our understanding of CD8+ Tregs is limited while they are …
immune tolerance; however, our understanding of CD8+ Tregs is limited while they are …
Regulatory T cells: molecular and cellular basis for immunoregulation
Y Togashi, H Nishikawa - … Targeting Immune Checkpoints in Cancer and …, 2017 - Springer
CD4+ regulatory T cells (Tregs) are a highly immune-suppressive subset of CD4+ T cells,
characterized by expression of the master regulatory transcription factor FOXP3. Tregs are …
characterized by expression of the master regulatory transcription factor FOXP3. Tregs are …
Soybean meal-induced intestinal inflammation in zebrafish is T cell-dependent and has a Th17 cytokine profile
M Coronado, CJ Solis, PP Hernandez… - Frontiers in …, 2019 - frontiersin.org
Currently, inflammatory bowel disease (IBD) is a serious public health problem on the rise
worldwide. In this work, we utilized the zebrafish to introduce a new model of intestinal …
worldwide. In this work, we utilized the zebrafish to introduce a new model of intestinal …
Engineered tolerance: tailoring development, function, and antigen-specificity of regulatory T cells
Regulatory T cells (Tregs) are potent suppressors of immune responses and are currently
being clinically tested for their potential to stop or control undesired immune responses in …
being clinically tested for their potential to stop or control undesired immune responses in …