[PDF][PDF] Building the neuronal microtubule cytoskeleton
LC Kapitein, CC Hoogenraad - Neuron, 2015 - cell.com
Microtubules are one of the major cytoskeletal components of neurons, essential for many
fundamental cellular and developmental processes, such as neuronal migration, polarity …
fundamental cellular and developmental processes, such as neuronal migration, polarity …
[PDF][PDF] Axonal transport: cargo-specific mechanisms of motility and regulation
S Maday, AE Twelvetrees, AJ Moughamian… - Neuron, 2014 - cell.com
Axonal transport is essential for neuronal function, and many neurodevelopmental and
neurodegenerative diseases result from mutations in the axonal transport machinery …
neurodegenerative diseases result from mutations in the axonal transport machinery …
[HTML][HTML] The role of the microtubule cytoskeleton in neurodevelopmental disorders
M Lasser, J Tiber, LA Lowery - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Neurons depend on the highly dynamic microtubule (MT) cytoskeleton for many different
processes during early embryonic development including cell division and migration …
processes during early embryonic development including cell division and migration …
Microtubule-based transport–basic mechanisms, traffic rules and role in neurological pathogenesis
MAM Franker, CC Hoogenraad - Journal of cell science, 2013 - journals.biologists.com
Microtubule-based transport is essential for neuronal function because of the large
distances that must be traveled by various building blocks and cellular materials. Recent …
distances that must be traveled by various building blocks and cellular materials. Recent …
[PDF][PDF] Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development
KW Yau, SFB van Beuningen, I Cunha-Ferreira… - Neuron, 2014 - cell.com
In neurons, most microtubules are not associated with a central microtubule-organizing
center (MTOC), and therefore, both the minus and plus-ends of these noncentrosomal …
center (MTOC), and therefore, both the minus and plus-ends of these noncentrosomal …
Dendrites in vitro and in vivo contain microtubules of opposite polarity and axon formation correlates with uniform plus-end-out microtubule orientation
KW Yau, P Schätzle, E Tortosa, S Pagès… - Journal of …, 2016 - Soc Neuroscience
In cultured vertebrate neurons, axons have a uniform arrangement of microtubules with plus-
ends distal to the cell body (plus-end-out), whereas dendrites contain mixed polarity …
ends distal to the cell body (plus-end-out), whereas dendrites contain mixed polarity …
Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity
C Sánchez-Huertas, F Freixo, R Viais, C Lacasa… - Nature …, 2016 - nature.com
Neurons display a highly polarized microtubule network that mediates trafficking throughout
the extensive cytoplasm and is crucial for neuronal differentiation and function. In newborn …
the extensive cytoplasm and is crucial for neuronal differentiation and function. In newborn …
The nano-architecture of the axonal cytoskeleton
The corporeal beauty of the neuronal cytoskeleton has captured the imagination of
generations of scientists. One of the easiest cellular structures to visualize by light …
generations of scientists. One of the easiest cellular structures to visualize by light …
CEP128 is involved in spermatogenesis in humans and mice
X Zhang, L Wang, Y Ma, Y Wang, H Liu, M Liu… - Nature …, 2022 - nature.com
Centrosomal proteins are necessary components of the centrosome, a conserved eukaryotic
organelle essential to the reproductive process. However, few centrosomal proteins have …
organelle essential to the reproductive process. However, few centrosomal proteins have …
Apical abscission alters cell polarity and dismantles the primary cilium during neurogenesis
Withdrawal of differentiating cells from proliferative tissue is critical for embryonic
development and adult tissue homeostasis; however, the mechanisms that control this cell …
development and adult tissue homeostasis; however, the mechanisms that control this cell …