Pituitary adenomas (PAs) are neoplasms derived from the endocrine cells of the anterior
pituitary gland. Most frequently, they are benign tumors, but may sometimes display an …

The pituitary tumour microenvironment encompasses a spectrum of non-tumoural cells, such
as immune, stromal or endothelial cells, as well as enzymes and signalling peptides like …

The microenvironment of pituitary adenomas (PAs) includes a range of non-tumoral cells,
such as immune and stromal cells, as well as cell signaling molecules such as cytokines …

Pituitary tumors are rare neoplasms, with a heterogeneous biological and clinical behavior,
due to their clinical course, local invasive growth, resistance to conventional therapies and …

Somatotropinomas are pituitary tumors with a heterogenous clinical behavior. The tumor
microenvironment regulates the interaction between tumor cells and the host immune …

Context Pituitary adenoma (PA) is a common intracranial tumor. The evidence indicates that
the tumor immune microenvironment (TIME) is associated with PA and that the intestinal …

Macrophages are one of the most common infiltrating immune cells and an essential
component of tumor microenvironment. Macrophages and the soluble cytokines and …

Recently, advances in molecular biology and bioinformatics have allowed a more thorough
understanding of tumorigenesis in aggressive PitNETs (pituitary neuroendocrine tumors) …

Simple Summary Pituitary neuroendocrine tumors are non-cancerous tumors of the pituitary
gland, that may overproduce hormones leading to serious health conditions or due to tumor …

Objective To investigate the levels of tumor-infiltrating CD8+ lymphocytes (CD8+ TILs) and
the expression of programmed cell death receptor ligand 1 (PD-L1) in the tumor …