[HTML][HTML] Mitochondrial quality control in diabetic cardiomyopathy: from molecular mechanisms to therapeutic strategies

C Cai, F Wu, J He, Y Zhang, N Shi, X Peng… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
In diabetic cardiomyopathy (DCM), a major diabetic complication, the myocardium is
structurally and functionally altered without evidence of coronary artery disease …

Myocardial ischemia-reperfusion injury; Molecular mechanisms and prevention

Y Liu, L Li, Z Wang, J Zhang, Z Zhou - Microvascular Research, 2023 - Elsevier
Cardiovascular diseases are one of the leading causes of mortality in developed countries.
Among cardiovascular disorders, myocardial infarction remains a life-threatening problem …

[HTML][HTML] Targeting mitochondrial quality control for diabetic cardiomyopathy: therapeutic potential of hypoglycemic drugs

Y Zhou, W Suo, X Zhang, J Liang, W Zhao… - Biomedicine & …, 2023 - Elsevier
Diabetic cardiomyopathy is a chronic cardiovascular complication caused by diabetes that is
characterized by changes in myocardial structure and function, ultimately leading to heart …

Mitochondrial quality control in cardiac ischemia/reperfusion injury: new insights into mechanisms and implications

Y Bai, J Wu, Z Yang, X Wang, D Zhang, J Ma - Cell Biology and Toxicology, 2023 - Springer
The current effective method for the treatment of myocardial infarction is timely restoration of
the blood supply to the ischemic area of the heart. Although reperfusion is essential for …

Extracellular vesicles derived from mesenchymal stromal cells delivered during hypothermic oxygenated machine perfusion repair ischemic/reperfusion damage of …

T Rampino, M Gregorini, G Germinario, EF Pattonieri… - Biology, 2022 - mdpi.com
Simple Summary In this study, we explore for the first time an innovative tool for organ
preservation aimed to preventing ischemia reperfusion injury (IRI) in marginal kidneys from …

Cardioprotective potential of vanillic acid

B Yalameha, HR Nejabati… - Clinical and Experimental …, 2023 - Wiley Online Library
Nowadays, cardiovascular diseases (CVDs) are a global threat to public health, accounting
for almost one‐third of all deaths worldwide. One of the key mechanistic pathways …

[HTML][HTML] Kallistatin/Serpina3c inhibits cardiac fibrosis after myocardial infarction by regulating glycolysis via Nr4a1 activation

J Ji, L Qian, Y Zhu, Y Jiang, J Guo, Y Wu, Z Yang… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Background Fibrotic remodeling is an essential aspect of heart failure. Human kallistatin
(KS, mouse Serpina3c homologs) inhibits fibrosis after myocardial infarction (MI) but the …

TCH-165 attenuates cardiac ischaemia/reperfusion injury by balancing mitochondrial dynamics via increasing proteasome activity

J Gao, HX Su, PB Li, KN Shi, HH Li - European Journal of Pharmacology, 2023 - Elsevier
The proteasome is the main complex responsible for maintaining intracellular protein
homeostasis, impairment of which is associated with cardiac ischaemia/reperfusion (I/R) …

[Retracted] Melatonin Attenuates Ischemia/Reperfusion‐Induced Oxidative Stress by Activating Mitochondrial Fusion in Cardiomyocytes

X Ma, S Wang, H Cheng, H Ouyang… - Oxidative Medicine and …, 2022 - Wiley Online Library
Myocardial ischemia/reperfusion (I/R) injury can stimulate mitochondrial reactive oxygen
species production. Optic atrophy 1‐(OPA1‐) induced mitochondrial fusion is an …

Modification of ischemia/reperfusion-induced alterations in subcellular organelles by ischemic preconditioning

PS Tappia, AK Shah, B Ramjiawan… - International Journal of …, 2022 - mdpi.com
It is now well established that ischemia/reperfusion (I/R) injury is associated with the
compromised recovery of cardiac contractile function. Such an adverse effect of I/R injury in …