Ambient particulate matter (PM) is an environmental factor that has been associated with
increased respiratory morbidity and mortality. The major effect of ambient PM on the …

Asthma is a chronic inflammatory disease, which involves a variety of different mediators,
including reactive oxygen species. There is growing awareness that particulate pollutants …

Eosinophil cationic proteins influence several biological functions of the respiratory
epithelium, yet their direct contribution to airway remodeling has not been established. We …

Exhaust emissions of eight Euro 6 light duty vehicles–two station wagons and six vans–half
powered by diesel fuel and half by compressed natural gas (CNG) were examined using …

Pulmonary cavitation is vital to the persistence and spread of Mycobacterium tuberculosis
(MTb), but mechanisms underlying this lung destruction are poorly understood. Fibrillar type …

Background Diesel exhaust particles (DEP) are a major component of outdoor air pollution.
DEP mediated pulmonary effects are plausibly linked to inflammatory and oxidative stress …

In healthy subjects, the respiratory epithelium forms a continuous lining to the airways and to
the environment, and plays a unique role as a barrier against external deleterious agents to …

Background Using an in vitro triple cell co-culture model consisting of human epithelial cells
(16HBE14o-), monocyte-derived macrophages and dendritic cells, it was recently …

Diesel fuel and the products of its combustion represent one of the toxins most commonly
encountered by people living in both urban and rural areas of the world. As nations become …

The purpose of this review is to stimulate new ideas regarding low-dose environmental
mixtures and carcinogens and their potential to promote invasion and metastasis. Whereas …