Viral meningitis and encephalitis: an update
V Gundamraj, R Hasbun - Current opinion in infectious diseases, 2023 - journals.lww.com
Viral meningitis and encephalitis: an update : Current Opinion in Infectious Diseases Viral
meningitis and encephalitis: an update : Current Opinion in Infectious Diseases Log in or …
meningitis and encephalitis: an update : Current Opinion in Infectious Diseases Log in or …
[HTML][HTML] Host–Pathogen interactions influencing zoonotic spillover potential and transmission in humans
Emerging infectious diseases of zoonotic origin are an ever-increasing public health risk
and economic burden. The factors that determine if and when an animal virus is able to spill …
and economic burden. The factors that determine if and when an animal virus is able to spill …
[HTML][HTML] Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection
M Ferren, V Favède, D Decimo, M Iampietro… - Nature …, 2021 - nature.com
SARS-CoV-2 has caused a global pandemic of COVID-19 since its emergence in December
2019. The infection causes a severe acute respiratory syndrome and may also spread to …
2019. The infection causes a severe acute respiratory syndrome and may also spread to …
[HTML][HTML] Impairment of SARS-CoV-2 spike glycoprotein maturation and fusion activity by nitazoxanide: an effect independent of spike variants emergence
A Riccio, S Santopolo, A Rossi, S Piacentini… - Cellular and Molecular …, 2022 - Springer
Abstract SARS-CoV-2, the causative agent of COVID-19, has caused an unprecedented
global health crisis. The SARS-CoV-2 spike, a surface-anchored trimeric class-I fusion …
global health crisis. The SARS-CoV-2 spike, a surface-anchored trimeric class-I fusion …
[PDF][PDF] Activation of cGAS/STING pathway upon paramyxovirus infection
M Iampietro, C Dumont, C Mathieu, J Spanier, J Robert… - Iscience, 2021 - cell.com
During inflammatory diseases, cancer, and infection, the cGAS/STING pathway is known to
recognize foreign or self-DNA in the cytosol and activate an innate immune response. Here …
recognize foreign or self-DNA in the cytosol and activate an innate immune response. Here …
Molecular features of the measles virus viral fusion complex that favor infection and spread in the brain
Measles virus (MeV) bearing a single amino acid change in the fusion protein (F)—L454W—
was isolated from two patients who died of MeV central nervous system (CNS) infection. This …
was isolated from two patients who died of MeV central nervous system (CNS) infection. This …
[PDF][PDF] Quantitative assays reveal cell fusion at minimal levels of SARS-CoV-2 spike protein and fusion from without
SA Theuerkauf, A Michels, V Riechert, TJ Maier, E Flory… - Iscience, 2021 - cell.com
Cell entry of the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is mediated by its spike protein S. As a main antigenic determinant, S protein is in focus of …
is mediated by its spike protein S. As a main antigenic determinant, S protein is in focus of …
[HTML][HTML] Platinum-Nucleos (t) ide Compounds as Possible Antimetabolites for Antitumor/Antiviral Therapy: Properties and Perspectives
F De Castro, E Stefàno, E De Luca, M Benedetti… - Pharmaceutics, 2023 - mdpi.com
Nucleoside analogues (NAs) are a family of compounds which include a variety of purine
and pyrimidine derivatives, widely used as anticancer and antiviral agents. For their ability to …
and pyrimidine derivatives, widely used as anticancer and antiviral agents. For their ability to …
Structure-guided paradigm shifts in flavivirus assembly and maturation mechanisms
The flavivirus genus encompasses more than 75 unique viruses, including dengue virus
which accounts for almost 390 million global infections annually. Flavivirus infection can …
which accounts for almost 390 million global infections annually. Flavivirus infection can …
[HTML][HTML] Evidence for the Effectiveness of Remdesivir (GS-5734), a Nucleoside-Analog Antiviral Drug in the Inhibition of IK (M) or IK (DR) and in the Stimulation of I …
Remdesivir (RDV, GS-5734), a broad-spectrum antiviral drug in the class of nucleotide
analogs, has been particularly tailored for treatment of coronavirus infections. However, to …
analogs, has been particularly tailored for treatment of coronavirus infections. However, to …