A narrative review of the role of common EGFR mutations in pathogenesis and treatment of non-small-cell lung carcinoma
M Sharma, DA Basu, S Nathany… - Cancer Research …, 2022 - journals.lww.com
Epidermal growth factor receptor (EGFR) mutant non-small-cell lung cancer (NSCLC) is an
important subtype of lung cancer. With the existing and ongoing research and multiple …
important subtype of lung cancer. With the existing and ongoing research and multiple …
[HTML][HTML] Testing modalities for ALK-driven lung cancer: A narrative review
S Nathany, M Sharma, U Batra - Cancer Research, Statistics, and …, 2023 - journals.lww.com
Anaplastic lymphoma kinase (ALK) rearranged non-small-cell lung cancer (NSCLC)
comprises a distinct molecular entity with a reported global prevalence of 5–7%. The …
comprises a distinct molecular entity with a reported global prevalence of 5–7%. The …
Uniqueness of lung cancer in Southeast Asia
Lung cancer varies between Caucasians and Asians. There have been differences recorded
in the epidemiology, genomics, standard therapies and outcomes, with variations according …
in the epidemiology, genomics, standard therapies and outcomes, with variations according …
[HTML][HTML] ALK-driven NSCLC: A narrative review-Part I
S Nathany, M Sharma, U Batra - Cancer Research, Statistics, and …, 2023 - journals.lww.com
Anaplastic lymphoma kinase (ALK)-rearranged non-small-cell lung cancer (NSCLC) is a
molecularly distinct subgroup of oncogene-addicted NSCLC, accounting for 3-5% of cases …
molecularly distinct subgroup of oncogene-addicted NSCLC, accounting for 3-5% of cases …
Lung cancer with dual EGFR and ALK driver alterations at baseline: a retrospective observational cohort study
The journey of a thousand miles in lung cancer therapy began with the discovery of
actionable genomic alterations. The two most well described molecular alterations are the …
actionable genomic alterations. The two most well described molecular alterations are the …
Identification of a rare EGFR exon 18 mutation in lung adenocarcinoma using targeted next-generation sequencing as a tool for precision medicine
P Jha, V Trivedi, R Biswal, P Chandrani… - Cancer Research …, 2023 - journals.lww.com
DISCUSSION Introduction to EGFR EGFR belongs to the erythroblastic leukemia viral
oncogene homolog (ERBB) family of receptor tyrosine kinases and is alternatively known as …
oncogene homolog (ERBB) family of receptor tyrosine kinases and is alternatively known as …
[HTML][HTML] Challenges and breakthroughs: ALK alteration detection in non-small-cell lung carcinoma
O Shetty - Cancer Research, Statistics, and Treatment, 2023 - journals.lww.com
In the quest to improve the diagnosis and treatment of non-small-cell lung carcinoma
(NSCLC), particularly in cases involving anaplastic lymphoma kinase (ALK) gene …
(NSCLC), particularly in cases involving anaplastic lymphoma kinase (ALK) gene …
Concurrent EGFR and PIK3CA mutations in non-small-cell lung cancer
Figure 1: The left panel shows the liver lesion while the right panel shows the lung window
of the scans at different time points.(a and b) The baseline imaging prior to starting …
of the scans at different time points.(a and b) The baseline imaging prior to starting …
A Comparative Study Evaluating the Quality of Life and Survival Outcomes in Patients Receiving Chemotherapy Versus Oral Tyrosine Kinase Inhibitor in the Third Line …
Introduction The outcomes in advanced NSCLC have improved owing to the availability of
more effective systemic and improved supportive care. This has increased the number of …
more effective systemic and improved supportive care. This has increased the number of …
[HTML][HTML] Molecular analysis for EGFR, ALK, and ROS1 alterations in over 3000 Indian patients with non-small-cell lung cancer: A retrospective observational study
S Munde, S Barodawala, K Lila, R Jatale… - Cancer Research …, 2024 - journals.lww.com
Background: Accurate molecular testing in non-small-cell lung cancer (NSCLC) is of
paramount importance for treatment, prediction, and prognostication. Objectives: We aimed …
paramount importance for treatment, prediction, and prognostication. Objectives: We aimed …