Breast cancer is the most common type of cancer found in women and today represents a
significant challenge to public health. With the latest breakthroughs in molecular biology and …

Abstract Development of biological targeted therapies and immune checkpoint inhibitors has
redefined the treatment for many cancers; however, the increasing use of new protocols has …

Pathogenic gain-of-function variants in the genes encoding phosphoinositide 3-kinase δ
(PI3Kδ) lead to accumulation of transitional B cells and senescent T cells, lymphadenopathy …

Endocrine Therapy for Hormone Receptor-Positive Metastatic Breast Cancer: American Society
of Clinical Oncology Guideline - University of Miami Logo image Menu Find research works …

Breast cancer is the most harmful malignancy in women worldwide. Therefore, in the current
study, we investigated the combinatory effect of natural bioactive compounds, including …

Modern cancer therapeutics are increasingly targeted, bringing the promise of new and
improved activity, alongside better tolerability. However, while many are indeed resulting in …

Aromatase inhibitors (AIs) are anti-tumor agents used in clinic to treat hormone-dependent
breast cancer. AIs block estrogens biosynthesis by inhibiting the enzyme aromatase …

Four cardiac hormones, namely atrial natriuretic peptide, vessel dilator, kaliuretic peptide,
and long-acting natriuretic peptide, reduce up to 97% of all cancer cells in vitro. These four …

Immunosuppressant is a class of medicines that inhibit or decrease the intensity of the
immune response in the body. Most of these medications are used to allow the body less …

Most patients diagnosed with luminal metastatic breast cancer (MBC) who are seen in
oncology consultations are elderly. MBC in elderly patients is characterized by a higher …