Platelets are important actors of cardiovascular diseases (CVD). Current antiplatelet drugs
that inhibit platelet aggregation have been shown to be effective in CVD treatment. However …

Coronary no-reflow (CNR) is a frequent phenomenon that develops in patients with ST-
segment elevation myocardial infarction (STEMI) following reperfusion therapy. CNR is …

Background: Sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) is a key protein that
maintains myocardial Ca2+ homeostasis. The present study aimed to investigate the …

Coronary artery occlusion (45 min) and reperfusion (2 h) was performed in rats anesthetized
with α-chloralose. Opioid receptor agonists were administered intravenously 5 min before …

Introduction: Tanshinone IIA (Tan IIA), the major active lipophilic ingredient of Radix Salviae
Miltiorrhizae, exerts various therapeutic effects on the cardiovascular system. We aimed to …

Myocardial ischemia/reperfusion (I/R) injury contributes to the pathogenesis of numerous
diseases. Based on its antioxidant and anti‑inflammatory effects, dimethyl fumarate (DMF) …

Myocardial ischemia/reperfusion (MI/R) triggers a complicated chain of inflammatory
reactions. Dexmedetomidine (Dex) has been reported to be important in myocardial …

Ischemic heart diseases such as myocardial infarction (MI) are the largest contributors to
cardiovascular disease worldwide. The resulting cardiac cell death impairs function of the …

Background Myocardial ischemia reperfusion injury (MIRI) is defined as tissue injury in the
pathological process of progressive aggravation in ischemic myocardium after the …

Ginkgolide B (GB) is an extract of dried Ginkgo biloba leaves and possesses various
pharmacological activities in the cardiovascular system. Herein, we aim to assess the …