[HTML][HTML] Where the genome meets the connectome: understanding how genes shape human brain connectivity

A Arnatkeviciute, BD Fulcher, MA Bellgrove, A Fornito - Neuroimage, 2021 - Elsevier
The integration of modern neuroimaging methods with genetically informative designs and
data can shed light on the molecular mechanisms underlying the structural and functional …

[HTML][HTML] Imaging transcriptomics of brain disorders

A Arnatkeviciute, BD Fulcher, MA Bellgrove… - … Psychiatry Global Open …, 2022 - Elsevier
Noninvasive neuroimaging is a powerful tool for quantifying diverse aspects of brain
structure and function in vivo, and it has been used extensively to map the neural changes …

Genome-wide analyses of individual differences in quantitatively assessed reading-and language-related skills in up to 34,000 people

E Eising, N Mirza-Schreiber… - Proceedings of the …, 2022 - National Acad Sciences
The use of spoken and written language is a fundamental human capacity. Individual
differences in reading-and language-related skills are influenced by genetic variation, with …

[HTML][HTML] Optimising a simple fully convolutional network for accurate brain age prediction in the pac 2019 challenge

W Gong, CF Beckmann, A Vedaldi, SM Smith… - Frontiers in …, 2021 - frontiersin.org
Brain age prediction from brain MRI scans not only helps improve brain ageing modelling
generally, but also provides benchmarks for predictive analysis methods. Brain-age delta …

Genetic basis to structural grey matter associations with chronic pain

SF Farrell, AI Campos, PF Kho, RMJ de Zoete… - Brain, 2021 - academic.oup.com
Structural neuroimaging studies of individuals with chronic pain conditions have often
observed decreased regional grey matter at a phenotypic level. However, it is not known if …

Evaluating brain structure traits as endophenotypes using polygenicity and discoverability

N Matoba, MI Love, JL Stein - Human Brain Mapping, 2022 - Wiley Online Library
Human brain structure traits have been hypothesized to be broad endophenotypes for
neuropsychiatric disorders, implying that brain structure traits are comparatively “closer to …

Multivariate analysis reveals shared genetic architecture of brain morphology and human behavior

R de Vlaming, EAW Slob, PR Jansen, A Dagher… - Communications …, 2021 - nature.com
Human variation in brain morphology and behavior are related and highly heritable. Yet, it is
largely unknown to what extent specific features of brain morphology and behavior are …

The morphometry of left cuneus mediating the genetic regulation on working memory

X He, X Li, J Fu, J Xu, H Liu, P Zhang, W Li… - Human brain …, 2021 - Wiley Online Library
Working memory is a basic human cognitive function. However, the genetic signatures and
their biological pathway remain poorly understood. In the present study, we tried to clarify …

Temporal mapping of derived high-frequency gene variants supports the mosaic nature of the evolution of Homo sapiens

A Andirkó, J Moriano, A Vitriolo, M Kuhlwilm, G Testa… - Scientific Reports, 2022 - nature.com
Large-scale estimations of the time of emergence of variants are essential to examine
hypotheses concerning human evolution with precision. Using an open repository of genetic …

Large-scale phenomic and genomic analysis of brain asymmetrical skew

XZ Kong, M Postema, D Schijven, AC Castillo… - Cerebral …, 2021 - academic.oup.com
The human cerebral hemispheres show a left–right asymmetrical torque pattern, which has
been claimed to be absent in chimpanzees. The functional significance and developmental …