Cancer statistics in 2018 highlight an 8.6 million incidence in female cancers, and 4.2 million
cancer deaths globally. Moreover, breast cancer is the most frequent malignancy in females …

Toxoplasma gondii (T. gondii) is a prevalent protozoan parasite of medical and veterinary
significance. It is the etiologic agent of toxoplasmosis, a neglected disease in which …

Tumor suppressor genes (TSGs) are a major type of gatekeeper genes in the cell growth. A
knowledgebase with the systematic collection and curation of TSGs in multiple cancer types …

Despite significant improvement in survival rates of patients with breast cancer, prognosis of
metastatic disease is still dismal. Cancer stem-like cells (CSC) are considered to play a role …

Tumor suppressor p53 plays a central role in tumor suppression. As a transcription factor,
p53 mainly exerts its tumor suppressive function through transcriptional regulation of many …

MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs that have been
found highly conserved among species. MiRNAs are able to negatively regulate gene …

Non-viral gene delivery vectors have lagged far behind viral ones in the current pipeline of
clinical trials of gene therapy nanomedicines. Even when non-viral nanovectors pose less …

Emerging chemotherapy drugs and targeted therapies have been widely applied in
anticancer treatment and have given oncologists a promising future. Nevertheless …

Background/Aims: Micro-RNA (miR)-146b-5p is overexpressed in papillary thyroid
carcinoma (PTC) and associated with extrathyroidal invasion and advanced tumor stage. In …

Chemotherapy has been widely used in treating cancer patients. Despite the tremendous
progress in cancer treatment achieved during the last decades, drug resistance still …