Neutrophil autophagy and NETosis in COVID-19: perspectives

R Zhang, C Sun, Y Han, L Huang, H Sheng, J Wang… - Autophagy, 2023 - Taylor & Francis
The COVID-19 pandemic has caused substantial losses worldwide in people's lives, health,
and property. Currently, COVID-19 is still prominent worldwide without any specific drug …

Tissue injury and leukocyte changes in post-acute sequelae of SARS-CoV-2: review of 2833 post-acute patient outcomes per immune dysregulation and microbial …

MS Islam, Z Wang, M Abdel-Mohsen… - Journal of Leukocyte …, 2023 - academic.oup.com
A significant number of persons with coronavirus disease 2019 (COVID-19) experience
persistent, recurrent, or new symptoms several months after the acute stage of severe acute …

[HTML][HTML] CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung inflammation

PS Sung, SP Yang, YC Peng, CP Sun, MH Tao… - Journal of Biomedical …, 2022 - Springer
Background Coronavirus-induced disease 19 (COVID-19) infects more than three hundred
and sixty million patients worldwide, and people with severe symptoms frequently die of …

[HTML][HTML] Coronavirus disease 2019 (COVID-19) coronary vascular thrombosis: correlation with neutrophil but not endothelial activation

JE Johnson, D McGuone, ML Xu, D Jane-Wit… - The American Journal of …, 2022 - Elsevier
Severe coronavirus disease 2019 (COVID-19) increases the risk of myocardial injury that
contributes to mortality. This study used multiparameter immunofluorescence to extensively …

[HTML][HTML] SARS-CoV-2 infection of human lung epithelial cells induces TMPRSS-mediated acute fibrin deposition

R Erickson, C Huang, C Allen, J Ireland, G Roth… - Nature …, 2023 - nature.com
Severe COVID-associated lung injury is a major confounding factor of hospitalizations and
death with no effective treatments. Here, we describe a non-classical fibrin clotting …

[HTML][HTML] Host liver-derived extracellular vesicles deliver miR-142a-3p induces neutrophil extracellular traps via targeting WASL to block the development of …

L Wang, Z Zhu, Y Liao, L Zhang, Z Yu, R Yang, J Wu… - Molecular Therapy, 2022 - cell.com
Schistosomiasis is an important neglected tropical disease. Interactions between the host
immune system and schistosomes are complex. Neutrophils contribute to clearance of large …

[HTML][HTML] Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement …

F Ciccosanti, M Antonioli, A Sacchi, S Notari, A Farina… - Clinical proteomics, 2022 - Springer
Most patients infected with SARS-CoV-2 display mild symptoms with good prognosis, while
20% of patients suffer from severe viral pneumonia and up to 5% may require intensive care …

[HTML][HTML] Neutrophil extracellular traps, sepsis and COVID-19–a tripod stand

E Ventura-Santana, JR Ninan, CM Snyder… - Frontiers in …, 2022 - frontiersin.org
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible
for the current coronavirus disease 2019 (COVID-19) pandemic. Majority of COVID-19 …

The innate immune response, microenvironment proteinases, and the COVID-19 pandemic: pathophysiologic mechanisms and emerging therapeutic targets

MD Hollenberg, M Epstein - Kidney international supplements, 2022 - Elsevier
The coronavirus disease 2019 (COVID-19) pandemic, causing considerable mortality and
morbidity worldwide, has fully engaged the biomedical community in attempts to elucidate …

[HTML][HTML] Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID

AS Naidu, CK Wang, P Rao, F Mancini… - npj Science of …, 2024 - nature.com
Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …